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    Dpy19l3 dpy-19 like C-mannosyltransferase 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308519, updated on 13-Apr-2024

    Summary

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    Official Symbol
    Dpy19l3provided by RGD
    Official Full Name
    dpy-19 like C-mannosyltransferase 3provided by RGD
    Primary source
    RGD:1308334
    See related
    Ensembl:ENSRNOG00000021573 AllianceGenome:RGD:1308334
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308334
    Summary
    Predicted to enable mannosyltransferase activity. Predicted to be involved in protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan. Predicted to be integral component of membrane. Predicted to be active in nuclear inner membrane. Orthologous to human DPY19L3 (dpy-19 like C-mannosyltransferase 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Liver (RPKM 124.2), Kidney (RPKM 94.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Dpy19l3 in Genome Data Viewer
    Location:
    1q21
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (97487206..97554232, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (88350303..88417339, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (92002927..92069855, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 27 Neighboring gene programmed cell death 5 Neighboring gene uncharacterized LOC134483099 Neighboring gene zinc finger protein 507 Neighboring gene uncharacterized LOC134484890

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables mannosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mannosyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nuclear inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    probable C-mannosyltransferase DPY19L3
    Names
    dpy-19-like 3
    protein dpy-19 homolog 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135835.2 → NP_001129307.2  probable C-mannosyltransferase DPY19L3

      See identical proteins and their annotated locations for NP_001129307.2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A6JAC6, D4A9G5
      Related
      ENSRNOP00000033949.3, ENSRNOT00000039115.4
      Conserved Domains (1) summary
      pfam10034
      Location:57 → 712
      Dpy19; Q-cell neuroblast polarization

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      97487206..97554232 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006228888.5 → XP_006228950.1  probable C-mannosyltransferase DPY19L3 isoform X1

      See identical proteins and their annotated locations for XP_006228950.1

      UniProtKB/TrEMBL
      A6JAC6, D4A9G5
      Conserved Domains (1) summary
      pfam10034
      Location:57 → 712
      Dpy19; Q-cell neuroblast polarization

    2. XM_006228889.5 → XP_006228951.1  probable C-mannosyltransferase DPY19L3 isoform X1

      See identical proteins and their annotated locations for XP_006228951.1

      UniProtKB/TrEMBL
      A6JAC6, D4A9G5
      Conserved Domains (1) summary
      pfam10034
      Location:57 → 712
      Dpy19; Q-cell neuroblast polarization

    3. XM_008759164.4 → XP_008757386.1  probable C-mannosyltransferase DPY19L3 isoform X3

      UniProtKB/TrEMBL
      A6JAC6
      Conserved Domains (1) summary
      pfam10034
      Location:1 → 589
      Dpy19; Q-cell neuroblast polarization

    4. XM_017589127.3 → XP_017444616.1  probable C-mannosyltransferase DPY19L3 isoform X2

      UniProtKB/TrEMBL
      A6JAC6
      Conserved Domains (1) summary
      pfam10034
      Location:1 → 611
      Dpy19; Q-cell neuroblast polarization
    Nucleotide Protein Strain
    Heading Accession and Version

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