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    Bod1l1 biorientation of chromosomes in cell division 1-like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 207118, updated on 6-Jun-2024

    Summary

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    Official Symbol
    Bod1l1provided by RGD
    Official Full Name
    biorientation of chromosomes in cell division 1-like 1provided by RGD
    Primary source
    RGD:621413
    See related
    Ensembl:ENSRNOG00000050437 AllianceGenome:RGD:621413
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Abp10; Bod1l; Abp-10
    Summary
    Predicted to enable protein phosphatase 2A binding activity and protein phosphatase inhibitor activity. Predicted to be involved in cellular response to DNA damage stimulus; negative regulation of phosphoprotein phosphatase activity; and replication fork processing. Predicted to be located in nucleoplasm. Predicted to be part of outer kinetochore. Predicted to be active in centrosome; spindle microtubule; and spindle pole. Orthologous to human BOD1L1 (biorientation of chromosomes in cell division 1 like 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 121.2), Lung (RPKM 115.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Bod1l1 in Genome Data Viewer
    Location:
    14q21
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (73320880..73375662)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (69108483..69163255)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (73738137..73792935)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene high mobility group box 2 like 2 Neighboring gene uncharacterized LOC120096625 Neighboring gene uncharacterized LOC108352768 Neighboring gene uncharacterized LOC102550431 Neighboring gene NK3 homeobox 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. BOD1L Is Required to Suppress Deleterious Resection of Stressed Replication Forks. Higgs MR, et al. Mol Cell, 2015 Aug 6. PMID 26166705
    2. Molecular cloning and characterization of annexin V-binding proteins with highly hydrophilic peptide structure. Ohsawa K, et al. J Neurochem, 1996 Jul. PMID 8667030
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in DNA damage response ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in replication fork processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in replication fork processing ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of Set1C/COMPASS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Set1C/COMPASS complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    biorientation of chromosomes in cell division protein 1-like 1
    Names
    annexin V-binding protein ABP-10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      73320880..73375662
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039092813.2 → XP_038948741.1  biorientation of chromosomes in cell division protein 1-like 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A1A3
      Conserved Domains (4) summary
      PTZ00121
      Location:287 → 1146
      PTZ00121; MAEBL; Provisional
      TIGR00927
      Location:1574 → 1818
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam05205
      Location:55 → 148
      COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1
      cl27929
      Location:2750 → 2929
      Pox_A30L_A26L; Orthopoxvirus A26L/A30L protein

    2. XM_039092815.2 → XP_038948743.1  biorientation of chromosomes in cell division protein 1-like 1 isoform X3

      UniProtKB/TrEMBL
      A0A8I6A1A3
      Conserved Domains (4) summary
      PTZ00121
      Location:287 → 1146
      PTZ00121; MAEBL; Provisional
      TIGR00927
      Location:1574 → 1808
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam05205
      Location:55 → 148
      COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1
      cl27929
      Location:2750 → 2929
      Pox_A30L_A26L; Orthopoxvirus A26L/A30L protein

    3. XM_039092814.2 → XP_038948742.1  biorientation of chromosomes in cell division protein 1-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I6A1A3, M0RC54
      Related
      ENSRNOP00000067163.3
      Conserved Domains (4) summary
      PTZ00121
      Location:287 → 1146
      PTZ00121; MAEBL; Provisional
      TIGR00927
      Location:1574 → 1818
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam05205
      Location:55 → 148
      COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1
      cl27929
      Location:2747 → 2926
      Pox_A30L_A26L; Orthopoxvirus A26L/A30L protein

    4. XM_039092816.2 → XP_038948744.1  biorientation of chromosomes in cell division protein 1-like 1 isoform X4

      UniProtKB/TrEMBL
      A0A8I6A1A3, A0A8I6A9H5
      Related
      ENSRNOP00000087813.1
      Conserved Domains (4) summary
      PTZ00121
      Location:287 → 1146
      PTZ00121; MAEBL; Provisional
      TIGR00927
      Location:1574 → 1808
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam05205
      Location:55 → 148
      COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1
      cl27929
      Location:2747 → 2926
      Pox_A30L_A26L; Orthopoxvirus A26L/A30L protein

    5. XM_039092817.2 → XP_038948745.1  biorientation of chromosomes in cell division protein 1-like 1 isoform X5

      UniProtKB/TrEMBL
      A0A8I6A1A3
      Conserved Domains (4) summary
      PTZ00121
      Location:287 → 1041
      PTZ00121; MAEBL; Provisional
      TIGR00927
      Location:1574 → 1818
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam05205
      Location:55 → 148
      COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1
      cl27929
      Location:2485 → 2664
      Pox_A30L_A26L; Orthopoxvirus A26L/A30L protein

    6. XM_039092818.2 → XP_038948746.1  biorientation of chromosomes in cell division protein 1-like 1 isoform X6

      UniProtKB/TrEMBL
      A0A8I6A1A3
      Conserved Domains (4) summary
      PTZ00121
      Location:287 → 1041
      PTZ00121; MAEBL; Provisional
      TIGR00927
      Location:1574 → 1818
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam05205
      Location:55 → 148
      COMPASS-Shg1; COMPASS (Complex proteins associated with Set1p) component shg1
      cl27929
      Location:2482 → 2661
      Pox_A30L_A26L; Orthopoxvirus A26L/A30L protein

    7. XM_063273779.1 → XP_063129849.1  biorientation of chromosomes in cell division protein 1-like 1 isoform X7

      UniProtKB/TrEMBL
      A0A8I6A1A3
    Nucleotide Protein Strain
    Heading Accession and Version

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