U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Slc35a3 solute carrier family 35 member A3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310808, updated on 2-May-2024

    Summary

    Official Symbol
    Slc35a3provided by RGD
    Official Full Name
    solute carrier family 35 member A3provided by RGD
    Primary source
    RGD:1308615
    See related
    Ensembl:ENSRNOG00000015502 AllianceGenome:RGD:1308615
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable UDP-galactose transmembrane transporter activity. Predicted to be involved in UDP-N-acetylglucosamine transmembrane transport. Predicted to be located in Golgi apparatus. Predicted to be integral component of Golgi membrane. Orthologous to human SLC35A3 (solute carrier family 35 member A3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 156.1), Lung (RPKM 139.1) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Slc35a3 in Genome Data Viewer
    Location:
    2q42
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (207305008..207344225, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (204620103..204659319, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (219705618..219741886, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 39 Neighboring gene tRNA methyltransferase 13 homolog Neighboring gene SAS-6 centriolar assembly protein Neighboring gene major facilitator superfamily domain containing 14A Neighboring gene uncharacterized LOC102548510 Neighboring gene amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase Neighboring gene uncharacterized LOC120100926

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables UDP-galactose transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables UDP-galactose transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables antiporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables pyrimidine nucleotide-sugar transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in UDP-N-acetylglucosamine transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in UDP-N-acetylglucosamine transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in UDP-galactose transmembrane import into Golgi lumen IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in pyrimidine nucleotide-sugar transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    UDP-N-acetylglucosamine transporter
    Names
    golgi UDP-GlcNAc transporter
    solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012082.1NP_001012082.1  UDP-N-acetylglucosamine transporter

      See identical proteins and their annotated locations for NP_001012082.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079371
      UniProtKB/Swiss-Prot
      Q6AXR5
      UniProtKB/TrEMBL
      A0A8I6A4I5, A6HVA6, A6HVA8
      Related
      ENSRNOP00000074264.1, ENSRNOT00000085122.2
      Conserved Domains (1) summary
      pfam04142
      Location:1314
      Nuc_sug_transp; Nucleotide-sugar transporter

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      207305008..207344225 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063281941.1XP_063138011.1  UDP-N-acetylglucosamine transporter isoform X1