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    Polr3e RNA polymerase III subunit E [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361640, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Polr3eprovided by RGD
    Official Full Name
    RNA polymerase III subunit Eprovided by RGD
    Primary source
    RGD:1308086
    See related
    Ensembl:ENSRNOG00000016960 AllianceGenome:RGD:1308086
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308086
    Summary
    Predicted to be involved in transcription, DNA-templated. Predicted to be located in nucleoplasm. Predicted to be part of RNA polymerase III complex. Orthologous to human POLR3E (RNA polymerase III subunit E). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Adrenal (RPKM 67.8), Spleen (RPKM 58.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Polr3e in Genome Data Viewer
    Location:
    1q36
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (184897383..184925547)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (175466091..175494679)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (190852954..190881539)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102556194 Neighboring gene eukaryotic elongation factor-2 kinase Neighboring gene transfer RNA leucine (anticodon AAG) 1 Neighboring gene cerebellar degeneration-related protein 2 Neighboring gene small nucleolar RNA SNORA21 Neighboring gene major facilitator superfamily domain containing 13B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Cell growth- and differentiation-dependent regulation of RNA polymerase III transcription. Dumay-Odelot H, et al. Cell Cycle, 2010 Sep 15. PMID 20890107, Free PMC Article
    2. Gene duplication and neofunctionalization: POLR3G and POLR3GL. Renaud M, et al. Genome Res, 2014 Jan. PMID 24107381, Free PMC Article
    3. Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits. Hu P, et al. Mol Cell Biol, 2002 Nov. PMID 12391170, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in tRNA transcription by RNA polymerase III IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of RNA polymerase III complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase III complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    DNA-directed RNA polymerase III subunit RPC5
    Names
    RNA polymerase III polypeptide E
    polymerase (RNA) III (DNA directed) polypeptide E
    polymerase (RNA) III subunit E

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108503.1 → NP_001101973.1  DNA-directed RNA polymerase III subunit RPC5

      See identical proteins and their annotated locations for NP_001101973.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473956
      UniProtKB/TrEMBL
      A0A8I5ZZA4, A0A8I6AND9, A6I8T2, D3ZP45
      Related
      ENSRNOP00000046447.3, ENSRNOT00000040963.4
      Conserved Domains (1) summary
      pfam04801
      Location:5 → 432
      Sin_N; Sin-like protein conserved region

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      184897383..184925547
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006230168.5 → XP_006230230.1  DNA-directed RNA polymerase III subunit RPC5 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZZA4, A0A8I6AND9
      Related
      ENSRNOP00000085472.1
      Conserved Domains (1) summary
      pfam04801
      Location:5 → 431
      Sin_N; Sin-like protein conserved region

    2. XM_039082865.2 → XP_038938793.1  DNA-directed RNA polymerase III subunit RPC5 isoform X2

      Conserved Domains (1) summary
      pfam04801
      Location:5 → 356
      Sin_N; Sin-like protein conserved region
    Nucleotide Protein Strain
    Heading Accession and Version

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