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    Aspdh aspartate dehydrogenase domain containing [ Mus musculus (house mouse) ]

    Gene ID: 68352, updated on 5-Mar-2024

    Summary

    Official Symbol
    Aspdhprovided by MGI
    Official Full Name
    aspartate dehydrogenase domain containingprovided by MGI
    Primary source
    MGI:MGI:1915602
    See related
    Ensembl:ENSMUSG00000038704 AllianceGenome:MGI:1915602
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    0610012D14Rik
    Summary
    Predicted to enable NADP binding activity and aspartate dehydrogenase activity. Predicted to be involved in NAD biosynthetic process. Predicted to act upstream of or within pyridine nucleotide biosynthetic process. Orthologous to human ASPDH (aspartate dehydrogenase domain containing). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in liver adult (RPKM 186.3), kidney adult (RPKM 84.0) and 1 other tissue See more
    Orthologs
    NEW
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    Genomic context

    See Aspdh in Genome Data Viewer
    Location:
    7 B3; 7 28.83 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (44114859..44117175)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (44465435..44467751)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 39002 Neighboring gene leucine rich repeat containing 4B Neighboring gene predicted gene, 39003 Neighboring gene STARR-positive B cell enhancer ABC_E9110 Neighboring gene Josephin domain containing 2 Neighboring gene microRNA 7052 Neighboring gene RIKEN cDNA 5430431A17 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables NADP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables aspartate dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in NAD biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    aspartate dehydrogenase domain-containing protein
    Names
    putative L-aspartate dehydrogenase
    NP_080966.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026690.1NP_080966.1  aspartate dehydrogenase domain-containing protein

      See identical proteins and their annotated locations for NP_080966.1

      Status: PROVISIONAL

      Source sequence(s)
      AK002587
      Consensus CDS
      CCDS21207.1
      UniProtKB/Swiss-Prot
      Q8VCQ0, Q9DCQ2
      UniProtKB/TrEMBL
      D3Z253
      Related
      ENSMUSP00000039202.5, ENSMUST00000035929.11
      Conserved Domains (2) summary
      pfam01958
      Location:176265
      DUF108; Domain of unknown function DUF108
      pfam03447
      Location:17127
      NAD_binding_3; Homoserine dehydrogenase, NAD binding domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      44114859..44117175
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)