Dpy19l1 dpy-19 like C-mannosyltransferase 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Dpy19l1provided by RGD
Official Full Name: dpy-19 like C-mannosyltransferase 1provided by RGD
Primary source: RGD:1305822
See related: Ensembl:ENSRNOG00000026589 AllianceGenome:RGD:1305822
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1305822
Summary: Predicted to enable mannosyltransferase activity. Predicted to be involved in protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan. Predicted to be integral component of membrane. Predicted to be active in nuclear inner membrane. Orthologous to human DPY19L1 (dpy-19 like C-mannosyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Brain (RPKM 181.0), Spleen (RPKM 139.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 8q13

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (31209025..31297485, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (22933163..23021461, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (25582938..25669394, complement)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables mannosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in nuclear inner membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: protein C-mannosyl-transferase DPY19L1

Names: dpy-19 like 1; dpy-19-like protein 1; probable C-mannosyltransferase DPY19L1; protein dpy-19 homolog 1

NP_001178720.1

EC 2.4.1.-

XP_038937290.1

EC 2.4.1.-

XP_038937291.1

EC 2.4.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191791.2 → NP_001178720.1 protein C-mannosyl-transferase DPY19L1

See identical proteins and their annotated locations for NP_001178720.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000008

UniProtKB/Swiss-Prot

D4AD75

UniProtKB/TrEMBL

A0A8I6G3Y6

Related

ENSRNOP00000033222.4, ENSRNOT00000036738.7

Conserved Domains (1) summary

pfam10034
Location:105 → 743

Dpy19; Q-cell neuroblast polarisation
NM_001429803.1 → NP_001416732.1 protein C-mannosyl-transferase DPY19L1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000008

UniProtKB/Swiss-Prot

D4AD75

UniProtKB/TrEMBL

A0A8I6G3Y6

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086026.1 Reference GRCr8

Range

31209025..31297485 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039081362.2 → XP_038937290.1 protein C-mannosyl-transferase DPY19L1 isoform X1

Conserved Domains (1) summary

pfam10034
Location:105 → 743

Dpy19; Q-cell neuroblast polarisation
XM_039081363.2 → XP_038937291.1 protein C-mannosyl-transferase DPY19L1 isoform X2

Conserved Domains (1) summary

pfam10034
Location:1 → 587

Dpy19; Q-cell neuroblast polarisation