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    COL11A2 collagen type XI alpha 2 chain [ Bos taurus (cattle) ]

    Gene ID: 515435, updated on 6-Jun-2024

    Summary

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    Official Symbol
    COL11A2provided by VGNC
    Official Full Name
    collagen type XI alpha 2 chainprovided by VGNC
    Primary source
    VGNC:VGNC:27554
    See related
    Ensembl:ENSBTAG00000000601
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See COL11A2 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    67
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (7349362..7378844, complement)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene bromodomain containing 2 Neighboring gene major histocompatibility complex, class II, DO alpha Neighboring gene uncharacterized LOC132343598 Neighboring gene retinoid X receptor beta Neighboring gene solute carrier family 39 member 7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparative analysis of the bovine MHC class IIb sequence identifies inversion breakpoints and three unexpected genes. Childers CP, et al. Anim Genet, 2006 Apr. PMID 16573526
    2. The collagen family members as cell adhesion proteins. Heino J. Bioessays, 2007 Oct. PMID 17876790
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables heparin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    collagen alpha-2(XI) chain
    Names
    collagen, type XI, alpha 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001046199.1 → NP_001039664.1  collagen alpha-2(XI) chain precursor

      See identical proteins and their annotated locations for NP_001039664.1

      Status: PROVISIONAL

      Source sequence(s)
      AY957499
      UniProtKB/Swiss-Prot
      Q32S24
      UniProtKB/TrEMBL
      F1MRP6
      Related
      ENSBTAP00000000793.5, ENSBTAT00000000793.7
      Conserved Domains (3) summary
      pfam01391
      Location:654 → 710
      Collagen; Collagen triple helix repeat (20 copies)
      smart00038
      Location:1540 → 1735
      COLFI; Fibrillar collagens C-terminal domain
      smart00210
      Location:31 → 213
      TSPN; Thrombospondin N-terminal -like domains

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      7349362..7378844 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024983579.2 → XP_024839347.1  collagen alpha-2(XI) chain isoform X1

      UniProtKB/TrEMBL
      F1MRP6
      Conserved Domains (4) summary
      pfam01391
      Location:712 → 768
      Collagen; Collagen triple helix repeat (20 copies)
      smart00038
      Location:1598 → 1793
      COLFI; Fibrillar collagens C-terminal domain
      smart00210
      Location:31 → 213
      TSPN; Thrombospondin N-terminal -like domains
      cl26386
      Location:296 → 662
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

    2. XM_005223247.5 → XP_005223304.1  collagen alpha-2(XI) chain isoform X8

      UniProtKB/TrEMBL
      A0AAA9U0X2, F1MRP6
      Related
      ENSBTAP00000102784.1, ENSBTAT00000104382.1
      Conserved Domains (3) summary
      pfam01391
      Location:547 → 603
      Collagen; Collagen triple helix repeat (20 copies)
      smart00038
      Location:1433 → 1628
      COLFI; Fibrillar collagens C-terminal domain
      smart00210
      Location:31 → 213
      TSPN; Thrombospondin N-terminal -like domains

    3. XM_005223246.5 → XP_005223303.1  collagen alpha-2(XI) chain isoform X7

      UniProtKB/TrEMBL
      A0AAA9TJC4, F1MRP6
      Related
      ENSBTAP00000098425.1, ENSBTAT00000093929.1
      Conserved Domains (3) summary
      pfam01391
      Location:568 → 624
      Collagen; Collagen triple helix repeat (20 copies)
      smart00038
      Location:1454 → 1649
      COLFI; Fibrillar collagens C-terminal domain
      smart00210
      Location:31 → 213
      TSPN; Thrombospondin N-terminal -like domains

    4. XM_010818042.4 → XP_010816344.1  collagen alpha-2(XI) chain isoform X4

      UniProtKB/TrEMBL
      A0AAA9RZS5, F1MRP6
      Related
      ENSBTAP00000075315.1, ENSBTAT00000122125.1
      Conserved Domains (3) summary
      pfam01391
      Location:628 → 684
      Collagen; Collagen triple helix repeat (20 copies)
      smart00038
      Location:1514 → 1709
      COLFI; Fibrillar collagens C-terminal domain
      smart00210
      Location:31 → 213
      TSPN; Thrombospondin N-terminal -like domains

    5. XM_010818041.4 → XP_010816343.1  collagen alpha-2(XI) chain isoform X3

      UniProtKB/TrEMBL
      F1MRP6
      Conserved Domains (3) summary
      pfam01391
      Location:631 → 687
      Collagen; Collagen triple helix repeat (20 copies)
      smart00038
      Location:1517 → 1712
      COLFI; Fibrillar collagens C-terminal domain
      smart00210
      Location:31 → 213
      TSPN; Thrombospondin N-terminal -like domains

    6. XM_024983580.2 → XP_024839348.1  collagen alpha-2(XI) chain isoform X2

      UniProtKB/TrEMBL
      F1MRP6
      Conserved Domains (4) summary
      pfam01391
      Location:652 → 708
      Collagen; Collagen triple helix repeat (20 copies)
      smart00038
      Location:1538 → 1733
      COLFI; Fibrillar collagens C-terminal domain
      smart00210
      Location:31 → 213
      TSPN; Thrombospondin N-terminal -like domains
      cl26386
      Location:236 → 602
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

    7. XM_024983581.2 → XP_024839349.1  collagen alpha-2(XI) chain isoform X6

      UniProtKB/TrEMBL
      F1MRP6
      Conserved Domains (3) summary
      pfam01391
      Location:573 → 629
      Collagen; Collagen triple helix repeat (20 copies)
      smart00038
      Location:1459 → 1654
      COLFI; Fibrillar collagens C-terminal domain
      smart00210
      Location:31 → 213
      TSPN; Thrombospondin N-terminal -like domains

    8. XM_059880333.1 → XP_059736316.1  collagen alpha-2(XI) chain isoform X5

      UniProtKB/TrEMBL
      F1MRP6
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q32S24.1 GenPept UniProtKB/Swiss-Prot:Q32S24

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