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    MYBPC1 myosin binding protein C1 [ Bos taurus (cattle) ]

    Gene ID: 510763, updated on 5-Mar-2024

    Summary

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    Official Symbol
    MYBPC1provided by VGNC
    Official Full Name
    myosin binding protein C1provided by VGNC
    Primary source
    VGNC:VGNC:31780
    See related
    Ensembl:ENSBTAG00000011392
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See MYBPC1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (65398341..65500282)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase subunit 6A1, mitochondrial-like Neighboring gene Spi-C transcription factor Neighboring gene uncharacterized LOC132345307 Neighboring gene choline phosphotransferase 1 Neighboring gene large ribosomal subunit protein uL22-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Association of expression levels in skeletal muscle and a SNP in the MYBPC1 gene with growth-related trait in Japanese Black beef cattle. Tong B, et al. J Genet, 2015 Mar. PMID 25846887
    2. Association of a single-nucleotide polymorphism in myosin-binding protein C, slow-type (MYBPC1) gene with marbling in Japanese Black beef cattle. Tong B, et al. Anim Genet, 2014 Aug. PMID 24810268
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Increase of the MYBPC1 expression level might lead to high growth performance in cattle.
      Title: Association of expression levels in skeletal muscle and a SNP in the MYBPC1 gene with growth-related trait in Japanese Black beef cattle.
    2. The NC_007303.5:g.70014208A>G SNP is associated with marbling in Japanese Black beef cattle, with the G allele resulting in high levels of marbling. This SNP might have an impact on MYBPC1 expression and marbling by affecting MYBPC1 promoter activity.
      Title: Association of a single-nucleotide polymorphism in myosin-binding protein C, slow-type (MYBPC1) gene with marbling in Japanese Black beef cattle.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC155210

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    myosin-binding protein C, slow-type
    Names
    myosin binding protein C, slow type

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110773.1 → NP_001104243.1  myosin-binding protein C, slow-type

      See identical proteins and their annotated locations for NP_001104243.1

      Status: PROVISIONAL

      Source sequence(s)
      BC149204
      UniProtKB/TrEMBL
      A6QP89
      Related
      ENSBTAP00000041206.2, ENSBTAT00000043649.3
      Conserved Domains (8) summary
      cd00096
      Location:1121 → 1186
      Ig; Immunoglobulin domain
      cd05894
      Location:588 → 673
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00408
      Location:413 → 471
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:591 → 673
      IG_like; Immunoglobulin like
      cd00063
      Location:677 → 766
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1104 → 1193
      I-set; Immunoglobulin I-set domain
      pfam00047
      Location:121 → 205
      ig; Immunoglobulin domain
      cl11960
      Location:914 → 985
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      65398341..65500282
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010805153.4 → XP_010803455.1  myosin-binding protein C, slow-type isoform X1

      Conserved Domains (8) summary
      cd00096
      Location:1115 → 1180
      Ig; Immunoglobulin domain
      cd05894
      Location:600 → 685
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00408
      Location:425 → 483
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:603 → 685
      IG_like; Immunoglobulin like
      cd00063
      Location:689 → 778
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1098 → 1187
      I-set; Immunoglobulin I-set domain
      pfam00047
      Location:133 → 217
      ig; Immunoglobulin domain
      cl11960
      Location:908 → 979
      Ig; Immunoglobulin domain

    2. XM_059886284.1 → XP_059742267.1  myosin-binding protein C, slow-type isoform X4

    3. XM_059886288.1 → XP_059742271.1  myosin-binding protein C, slow-type isoform X8

    4. XM_059886285.1 → XP_059742268.1  myosin-binding protein C, slow-type isoform X5

    5. XM_059886290.1 → XP_059742273.1  myosin-binding protein C, slow-type isoform X11

      Related
      ENSBTAP00000077663.1, ENSBTAT00000120180.1

    6. XM_059886286.1 → XP_059742269.1  myosin-binding protein C, slow-type isoform X6

    7. XM_059886287.1 → XP_059742270.1  myosin-binding protein C, slow-type isoform X7

    8. XM_059886289.1 → XP_059742272.1  myosin-binding protein C, slow-type isoform X10

      Related
      ENSBTAP00000078640.1, ENSBTAT00000104417.1

    9. XM_010805154.4 → XP_010803456.1  myosin-binding protein C, slow-type isoform X2

      Conserved Domains (8) summary
      cd00096
      Location:1115 → 1180
      Ig; Immunoglobulin domain
      cd05894
      Location:600 → 685
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00408
      Location:425 → 483
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:603 → 685
      IG_like; Immunoglobulin like
      cd00063
      Location:689 → 778
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1098 → 1187
      I-set; Immunoglobulin I-set domain
      pfam00047
      Location:133 → 217
      ig; Immunoglobulin domain
      cl11960
      Location:908 → 979
      Ig; Immunoglobulin domain

    10. XM_024991609.2 → XP_024847377.1  myosin-binding protein C, slow-type isoform X3

      Conserved Domains (7) summary
      cd05894
      Location:600 → 685
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00409
      Location:510 → 587
      IG; Immunoglobulin
      cd00063
      Location:689 → 778
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1098 → 1187
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:907 → 979
      Ig; Immunoglobulin domain
      cl25865
      Location:2 → 77
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      cl28434
      Location:410 → 497
      I-set; Immunoglobulin I-set domain

    11. XM_024991612.2 → XP_024847380.1  myosin-binding protein C, slow-type isoform X9

      Conserved Domains (8) summary
      cd05894
      Location:600 → 685
      Ig_C5_MyBP-C; C5 immunoglobulin (Ig) domain of cardiac myosin binding protein C (MyBP-C)
      smart00409
      Location:133 → 228
      IG; Immunoglobulin
      smart00410
      Location:510 → 587
      IG_like; Immunoglobulin like
      cd00063
      Location:689 → 778
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:1098 → 1187
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:907 → 979
      Ig; Immunoglobulin domain
      cl25865
      Location:2 → 77
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      cl28434
      Location:410 → 497
      I-set; Immunoglobulin I-set domain
    Nucleotide Protein Strain
    Heading Accession and Version

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