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    Snapc1 small nuclear RNA activating complex, polypeptide 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 314228, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Snapc1provided by RGD
    Official Full Name
    small nuclear RNA activating complex, polypeptide 1provided by RGD
    Primary source
    RGD:1304671
    See related
    Ensembl:ENSRNOG00000009296 AllianceGenome:RGD:1304671
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in snRNA transcription by RNA polymerase II and snRNA transcription by RNA polymerase III. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of snRNA-activating protein complex. Orthologous to human SNAPC1 (small nuclear RNA activating complex polypeptide 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Adrenal (RPKM 89.5), Kidney (RPKM 70.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Snapc1 in Genome Data Viewer
    Location:
    6q24
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (98420588..98442065)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (92684785..92710772)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (96871675..96893422)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene protein kinase C, eta Neighboring gene large ribosomal subunit protein eL8-like Neighboring gene uncharacterized LOC120103553 Neighboring gene transmembrane protein 183A, pseudogene 2 Neighboring gene hypoxia inducible factor 1 subunit alpha Neighboring gene uncharacterized LOC134479220 Neighboring gene synaptotagmin 16 Neighboring gene uncharacterized LOC102550910

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A structural perspective on RNA polymerase I and RNA polymerase III transcription machineries. Vannini A. Biochim Biophys Acta, 2013 Mar-Apr. PMID 23031840
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in snRNA transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in snRNA transcription by RNA polymerase III IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of snRNA-activating protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    snRNA-activating protein complex subunit 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108033.1 → NP_001101503.1  snRNA-activating protein complex subunit 1

      See identical proteins and their annotated locations for NP_001101503.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473947
      UniProtKB/TrEMBL
      B1WC17, F7ES94
      Related
      ENSRNOP00000012361.5, ENSRNOT00000012361.6
      Conserved Domains (1) summary
      pfam09808
      Location:26 → 210
      SNAPc_SNAP43; Small nuclear RNA activating complex (SNAPc), subunit SNAP43

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      98420588..98442065
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039112268.2 → XP_038968196.1  snRNA-activating protein complex subunit 1 isoform X1

      UniProtKB/TrEMBL
      F7ES94
      Conserved Domains (1) summary
      pfam09808
      Location:1 → 146
      SNAPc_SNAP43; Small nuclear RNA activating complex (SNAPc), subunit SNAP43
    Nucleotide Protein Strain
    Heading Accession and Version

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