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    PAR32 Par32p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851381, updated on 17-May-2024

    Summary

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    Gene symbol
    PAR32
    Gene description
    Par32p
    Primary source
    FungiDB:YDL173W
    Locus tag
    YDL173W
    See related
    SGD:S000002332; AllianceGenome:SGD:S000002332; VEuPathDB:YDL173W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    AMU1
    Summary
    Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See PAR32 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (148191..149078)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene TRAMP complex RNA-binding subunit Neighboring gene D-lactate dehydrogenase Neighboring gene glutamate synthase (NADH) Neighboring gene Uga3p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Saccharomyces cerevisiae nutrient signaling pathways show an unexpected early activation pattern during winemaking. Vallejo B, et al. Microb Cell Fact, 2020 Jun 6. PMID 32505207, Free PMC Article
    2. Feedback regulation of TORC1 by its downstream effectors Npr1 and Par32. Varlakhanova NV, et al. Mol Biol Cell, 2018 Nov 1. PMID 30156471, Free PMC Article
    3. Identification of a Novel Regulatory Mechanism of Nutrient Transport Controlled by TORC1-Npr1-Amu1/Par32. Boeckstaens M, et al. PLoS Genet, 2015 Jul. PMID 26172854, Free PMC Article
    4. A LAPF/phafin1-like protein regulates TORC1 and lysosomal membrane permeabilization in response to endoplasmic reticulum membrane stress. Kim A, et al. Mol Biol Cell, 2015 Dec 15. PMID 26510498, Free PMC Article
    5. A genome-wide screen in Saccharomyces cerevisiae reveals a critical role for the mitochondria in the toxicity of a trichothecene mycotoxin. McLaughlin JE, et al. Proc Natl Acad Sci U S A, 2009 Dec 22. PMID 20007368, Free PMC Article

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. This study identifies the function of Amu1/Par32 in acute control of ammonium transport in response to variations in nitrogen availability.
      Title: Identification of a Novel Regulatory Mechanism of Nutrient Transport Controlled by TORC1-Npr1-Amu1/Par32.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Par32p
    NP_010108.1
    • Low complexity protein; mediates inhibition of Mep1p and Mep3p activity; hyperphosphorylated upon rapamycin treatment in a Tap42p-dependent manner; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; phosphorylation and localization regulated by TORC1-effector kinase, Npr1p

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      148191..149078
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180233.1 → NP_010108.1  TPA: Par32p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010108.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRH9, Q12515, Q6Q543
      UniProtKB/TrEMBL
      A0A8H8UMC5, C7GL19, N1PAL0
      Conserved Domains (1) summary
      pfam12223
      Location:20 → 77
      DUF3602; Protein of unknown function (DUF3602)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12515.1

    Gene LinkOut

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