U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    AHC1 Ahc1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854188, updated on 17-May-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    AHC1
    Gene description
    Ahc1p
    Primary source
    FungiDB:YOR023C
    Locus tag
    YOR023C
    See related
    SGD:S000005549; AllianceGenome:SGD:S000005549; VEuPathDB:YOR023C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Contributes to histone acetyltransferase activity. Involved in histone acetylation and replication-born double-strand break repair via sister chromatid exchange. Part of ADA complex. [provided by Alliance of Genome Resources, Apr 2022]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See AHC1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (376012..377712, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene protein-arginine N-methyltransferase SFM1 Neighboring gene putative carboxylic ester hydrolase Neighboring gene NAD-dependent histone deacetylase HST3 Neighboring gene Bub3p

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Components of the SAGA histone acetyltransferase complex are required for repressed transcription of ARG1 in rich medium. Ricci AR, et al. Mol Cell Biol, 2002 Jun. PMID 12024017, Free PMC Article
    2. The ADA complex is a distinct histone acetyltransferase complex in Saccharomyces cerevisiae. Eberharter A, et al. Mol Cell Biol, 1999 Oct. PMID 10490601, Free PMC Article
    3. The Aurora-B-dependent NoCut checkpoint prevents damage of anaphase bridges after DNA replication stress. Amaral N, et al. Nat Cell Biol, 2016 May. PMID 27111841
    4. TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability. Germann SM, et al. J Cell Biol, 2014 Jan 6. PMID 24379413, Free PMC Article
    5. N-terminal domain of nuclear IL-1α shows structural similarity to the C-terminal domain of Snf1 and binds to the HAT/core module of the SAGA complex. Zamostna B, et al. PLoS One, 2012. PMID 22879895, Free PMC Article

    See all (51) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Chromatin regulator Ahc1p co-regulates nitrogen metabolism via interactions with multiple transcription factors in Saccharomyces cerevisiae.
      Title: Chromatin regulator Ahc1p co-regulates nitrogen metabolism via interactions with multiple transcription factors in Saccharomyces cerevisiae.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Process Evidence Code Pubs
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in replication-born double-strand break repair via sister chromatid exchange IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ADA complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Ahc1p
    NP_014666.1
    • Subunit of the Ada histone acetyltransferase complex; required for structural integrity of the complex; Ahc2p and Ahc1p are unique to the ADA complex and not shared with the related SAGA and SLIK complexes; Ahc2p may tether Ahc1p to the complex

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      376012..377712 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183442.1 → NP_014666.1  TPA: Ahc1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014666.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W290, Q12433
      UniProtKB/TrEMBL
      A0A6V8S035, C7GLF4, G2WMQ5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12433.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools