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    PCBP1-AS1 PCBP1 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 400960, updated on 6-Nov-2023

    Summary

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    Official Symbol
    PCBP1-AS1provided by HGNC
    Official Full Name
    PCBP1 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:42948
    See related
    Ensembl:ENSG00000179818 AllianceGenome:HGNC:42948
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    Linc-GALH
    Expression
    Ubiquitous expression in testis (RPKM 3.5), ovary (RPKM 2.9) and 24 other tissues See more
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    Genomic context

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    Location:
    2p13.3
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (69962263..70088208, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (69973985..70099932, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (70189395..70314147, complement)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11602 Neighboring gene Sharpr-MPRA regulatory region 10436 Neighboring gene MAX dimerization protein 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70164441-70164976 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:70173615-70174814 Neighboring gene aspartic peptidase retroviral like 1 Neighboring gene small nucleolar RNA U13 Neighboring gene Sharpr-MPRA regulatory region 1834 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70199285-70200162 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70202867-70203378 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70203379-70203889 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70211622-70212122 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70212123-70212623 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:70220299-70220798 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:70224580-70224834 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15983 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:70256223-70257094 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15984 Neighboring gene Sharpr-MPRA regulatory region 12254 Neighboring gene RNA, 7SL, cytoplasmic 470, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15986 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15987 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15988 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11603 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11604 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:70315031-70315675 Neighboring gene conserved acetylation island sequence C15 enhancer Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11605 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11606 Neighboring gene uncharacterized LOC124906022 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15989 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15990 Neighboring gene poly(rC) binding protein 1 Neighboring gene mitochondrial ribosomal protein L36 pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. LncRNA PCBP1-AS1 correlated with the functional states of cancer cells and inhibited lung adenocarcinoma metastasis by suppressing the EMT progression. Li Z, et al. Carcinogenesis, 2021 Jul 16. PMID 34107009
    2. The long non-coding RNA Linc-GALH promotes hepatocellular carcinoma metastasis via epigenetically regulating Gankyrin. Xu X, et al. Cell Death Dis, 2019 Jan 28. PMID 30692513, Free PMC Article
    3. lncRNA PCBP1-AS1 mediated downregulation of ITGAL as a prognostic biomarker in lung adenocarcinoma. Wang Q, et al. Aging (Albany NY), 2023 May 31. PMID 37256932, Free PMC Article
    4. Identification and evaluation of lncRNA and mRNA integrative modules in human peripheral blood mononuclear cells. Mo XB, et al. Epigenomics, 2017 Jul. PMID 28621149
    5. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. Navarini AA, et al. Nat Commun, 2014 Jun 13. PMID 24927181

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Association of LncRNA PCBP1-AS1 with cancer occurrence and development: A review.
      Title: Association of LncRNA PCBP1-AS1 with cancer occurrence and development: A review.
    2. LncRNA PCBP1-AS1 Induces Cerebral Ischemia/Reperfusion Injury via the miR-506-3p/CCL2 Axis.
      Title: LncRNA PCBP1-AS1 Induces Cerebral Ischemia/Reperfusion Injury via the miR-506-3p/CCL2 Axis.
    3. lncRNA PCBP1-AS1 mediated downregulation of ITGAL as a prognostic biomarker in lung adenocarcinoma.
      Title: lncRNA PCBP1-AS1 mediated downregulation of ITGAL as a prognostic biomarker in lung adenocarcinoma.
    4. LncRNA PCBP1-AS1 correlated with the functional states of cancer cells and inhibited lung adenocarcinoma metastasis by suppressing the EMT progression.
      Title: LncRNA PCBP1-AS1 correlated with the functional states of cancer cells and inhibited lung adenocarcinoma metastasis by suppressing the EMT progression.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Markers

    Potential readthrough

    Included gene: ASPRV1

    Other Names

    • Gankyrin Associated LincRNA in Hepatocellular carcinoma
    • PCBP1 antisense RNA 1 (non-protein coding)

    Clone Names

    • AC136007.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_033872.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AK308634, BC040598
      Related
      ENST00000435880.6

    2. NR_183088.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    3. NR_183089.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    4. NR_183090.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000684907.1

    5. NR_183091.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    6. NR_183092.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000653064.1

    7. NR_183093.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000657575.2

    8. NR_183094.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000702284.1

    9. NR_183095.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000659941.2

    10. NR_183096.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000661703.1

    11. NR_183097.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    12. NR_183098.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    13. NR_183099.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000669583.1

    14. NR_183100.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000668711.1

    15. NR_183101.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000654336.1

    16. NR_183102.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    17. NR_183103.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    18. NR_183104.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    19. NR_183105.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    20. NR_183106.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000653606.1

    21. NR_183107.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    22. NR_183108.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    23. NR_183109.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000653596.1

    24. NR_183110.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    25. NR_183111.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    26. NR_183112.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    27. NR_183113.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    28. NR_183114.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    29. NR_183115.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000666167.1

    30. NR_183116.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    31. NR_183117.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    32. NR_183118.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    33. NR_183119.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    34. NR_183120.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    35. NR_183121.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000655420.1

    36. NR_183122.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000666074.1

    37. NR_183123.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    38. NR_183124.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    39. NR_183125.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000655481.1

    40. NR_183126.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000702210.1

    41. NR_183127.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    42. NR_183129.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000416068.6

    43. NR_183130.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    44. NR_183131.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000612202.5

    45. NR_183132.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    46. NR_183133.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    47. NR_183134.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    48. NR_183135.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    49. NR_183136.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    50. NR_183137.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    51. NR_183138.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    52. NR_183139.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    53. NR_183140.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    54. NR_183141.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    55. NR_183142.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    56. NR_183143.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    57. NR_183144.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    58. NR_183145.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    59. NR_183146.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    60. NR_183147.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    61. NR_183148.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    62. NR_183150.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000654716.1

    63. NR_183151.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    64. NR_183152.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    65. NR_183153.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000664754.1

    66. NR_183154.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    67. NR_183155.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    68. NR_183156.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    69. NR_183157.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    70. NR_183158.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    71. NR_183159.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811
      Related
      ENST00000437019.2

    72. NR_183161.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    73. NR_183162.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    74. NR_183163.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    75. NR_183164.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    76. NR_183165.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    77. NR_183166.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    78. NR_183167.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    79. NR_183168.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    80. NR_183169.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    81. NR_183170.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    82. NR_183172.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    83. NR_183173.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC016700, AC079811

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      69962263..70088208 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      69973985..70099932 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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