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    icn2 ictacalcin 2 [ Danio rerio (zebrafish) ]

    Gene ID: 100005083, updated on 27-Mar-2024

    Summary

    Official Symbol
    icn2provided by ZNC
    Official Full Name
    ictacalcin 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070822-9
    See related
    Ensembl:ENSDARG00000055514 AllianceGenome:ZFIN:ZDB-GENE-070822-9
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:171263
    Summary
    Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Acts upstream of or within glial cell development and retina development in camera-type eye. Predicted to be active in cytoplasm. Is expressed in several structures, including digestive system; heart; integument; renal system; and sensory system. Orthologous to several human genes including S100A2 (S100 calcium binding protein A2) and S100A4 (S100 calcium binding protein A4). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See icn2 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (23487047..23491094)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (23572015..23576062)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene S100 calcium binding protein W Neighboring gene ictacalcin Neighboring gene sorting nexin 27b Neighboring gene adenosine deaminase RNA specific

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables calcium-dependent protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transition metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082957.2NP_001076426.1  ictacalcin 2

      See identical proteins and their annotated locations for NP_001076426.1

      Status: VALIDATED

      Source sequence(s)
      CR533578, EF396273, EH587094
      UniProtKB/TrEMBL
      A3FKT8, A7E2G6
      Related
      ENSDARP00000120686.1, ENSDART00000145496.2
      Conserved Domains (2) summary
      cd00213
      Location:693
      S-100; S-100: S-100 domain, which represents the largest family within the superfamily of proteins carrying the Ca-binding EF-hand motif. Note that this S-100 hierarchy contains only S-100 EF-hand domains, other EF-hands have been modeled separately. S100 ...
      pfam13499
      Location:3182
      EF-hand_7; EF-hand domain pair

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      23487047..23491094
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)