UBASH3B ubiquitin associated and SH3 domain containing B [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: UBASH3Bprovided by VGNC
Official Full Name: ubiquitin associated and SH3 domain containing Bprovided by VGNC
Primary source: VGNC:VGNC:79826
See related: Ensembl:ENSMMUG00000002919
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	14	NC_041767.1 (115647380..115806814)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	14	NC_027906.1 (115473444..115630112)

Chromosome 14 - NC_041767.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

SHGC-54247 (e-PCR)
- UniSTS:2948

D11S2064 (e-PCR)
- UniSTS:31132

RH99018 (e-PCR)
- UniSTS:90066

D11S1336 (e-PCR), detects polymorphism
- UniSTS:85981

G59531 (e-PCR)
- UniSTS:136693

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein tyrosine phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in collagen-activated tyrosine kinase receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of bone resorption	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of protein kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in peptidyl-tyrosine dephosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in platelet aggregation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of osteoclast differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of release of sequestered calcium ion into cytosol	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ubiquitin-associated and SH3 domain-containing protein B

NP_001248215.1

EC 3.1.3.48

XP_014971390.1

EC 3.1.3.48

XP_014971391.1

EC 3.1.3.48

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001261286.1 → NP_001248215.1 ubiquitin-associated and SH3 domain-containing protein B

See identical proteins and their annotated locations for NP_001248215.1

Status: PROVISIONAL

Source sequence(s)

JU477558

UniProtKB/TrEMBL

A0A1D5QQV1, F7H1S6

Related

ENSMMUP00000003908.4, ENSMMUT00000004142.4

Conserved Domains (3) summary

cd07067
Location:386 → 598

HP_PGM_like; Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction

cd11936
Location:256 → 317

SH3_UBASH3B; Src homology 3 domain of Ubiquitin-associated and SH3 domain-containing protein B

cd14301
Location:39 → 76

UBA_UBS3B; UBA domain found in ubiquitin-associated and SH3 domain-containing protein B (UBS3B) and similar proteins

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041767.1 Reference Mmul_10 Primary Assembly

Range

115647380..115806814

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015115905.2 → XP_014971391.1 ubiquitin-associated and SH3 domain-containing protein B isoform X2

Conserved Domains (2) summary

cd07067
Location:351 → 563

HP_PGM_like; Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction

cd11936
Location:221 → 282

SH3_UBASH3B; Src homology 3 domain of Ubiquitin-associated and SH3 domain-containing protein B
XM_015115904.2 → XP_014971390.1 ubiquitin-associated and SH3 domain-containing protein B isoform X1

Conserved Domains (2) summary

cd07067
Location:352 → 564

HP_PGM_like; Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction

cd11936
Location:222 → 283

SH3_UBASH3B; Src homology 3 domain of Ubiquitin-associated and SH3 domain-containing protein B