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    Tmem256 transmembrane protein 256 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287442, updated on 13-Apr-2024

    Summary

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    Official Symbol
    Tmem256provided by RGD
    Official Full Name
    transmembrane protein 256provided by RGD
    Primary source
    RGD:1563438
    See related
    Ensembl:ENSRNOG00000037540 AllianceGenome:RGD:1563438
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563438
    Summary
    Predicted to be integral component of membrane. Orthologous to human TMEM256 (transmembrane protein 256). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 457.1), Heart (RPKM 456.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem256 in Genome Data Viewer
    Location:
    10q24
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (55056959..55058869)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (54559030..54560146)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (56446022..56447138)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene spermatid maturation 1 Neighboring gene neuroligin 2 Neighboring gene phospholipid scramblase 3 Neighboring gene tyrosine kinase, non-receptor, 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Proteomic analysis of the mouse liver mitochondrial inner membrane. Da Cruz S, et al. J Biol Chem, 2003 Oct 17. PMID 12865426
    2. Large-scale proteomics and phosphoproteomics of urinary exosomes. Gonzales PA, et al. J Am Soc Nephrol, 2009 Feb. PMID 19056867, Free PMC Article
    3. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 256

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001170549.1 → NP_001164020.1  transmembrane protein 256

      See identical proteins and their annotated locations for NP_001164020.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A8I5YBI7, A6HFU3, F1LYI7
      Related
      ENSRNOP00000053711.2, ENSRNOT00000056870.5
      Conserved Domains (1) summary
      pfam04241
      Location:22 → 101
      DUF423; Protein of unknown function (DUF423)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      55056959..55058869
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063268641.1 → XP_063124711.1  transmembrane protein 256 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AIZ6

    2. XM_063268642.1 → XP_063124712.1  transmembrane protein 256 isoform X2

    3. XM_063268643.1 → XP_063124713.1  transmembrane protein 256 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

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