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    Fbxo33 F-box protein 33 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 314157, updated on 13-Apr-2024

    Summary

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    Official Symbol
    Fbxo33provided by RGD
    Official Full Name
    F-box protein 33provided by RGD
    Primary source
    RGD:1307543
    See related
    Ensembl:ENSRNOG00000005285 AllianceGenome:RGD:1307543
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in positive regulation of protein ubiquitination. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human FBXO33 (F-box protein 33). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Spleen (RPKM 96.6), Thymus (RPKM 94.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    6q23
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (82635509..82669441, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (76900619..76934232, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (80302291..80334536, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene pinin, desmosome associated protein Neighboring gene MIA SH3 domain ER export factor 2 Neighboring gene small nucleolar RNA, H/ACA box 26 like 1 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in positive regulation of protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    F-box only protein 33

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001399654.1 → NP_001386583.1  F-box only protein 33

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      Related
      ENSRNOP00000091589.1, ENSRNOT00000094790.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      82635509..82669441 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039112237.2 → XP_038968165.1  F-box only protein 33 isoform X1

    2. XM_039112238.2 → XP_038968166.1  F-box only protein 33 isoform X2

      Conserved Domains (1) summary
      pfam12937
      Location:72 → 111
      F-box-like

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001108023.1: Suppressed sequence

      Description
      NM_001108023.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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