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    Smim15 small integral membrane protein 15 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100359861, updated on 13-Apr-2024

    Summary

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    Official Symbol
    Smim15provided by RGD
    Official Full Name
    small integral membrane protein 15provided by RGD
    Primary source
    RGD:2324600
    See related
    Ensembl:ENSRNOG00000031995 AllianceGenome:RGD:2324600
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be integral component of membrane. Orthologous to human SMIM15 (small integral membrane protein 15). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 249.4), Spleen (RPKM 228.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Smim15 in Genome Data Viewer
    Location:
    2q14
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (41261710..41266870)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (39528256..39533416)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (39314714..39319874)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120100701 Neighboring gene uncharacterized LOC102549347 Neighboring gene uncharacterized LOC120100702 Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 2 Neighboring gene uncharacterized LOC134485832 Neighboring gene ERCC excision repair 8, CSA ubiquitin ligase complex subunit

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    small integral membrane protein 15
    Names
    mCG51409-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001277209.2 → NP_001264138.1  small integral membrane protein 15 isoform 1

      See identical proteins and their annotated locations for NP_001264138.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes isoform 1.
      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A6I5J6, D4A573
      Related
      ENSRNOP00000083129.1, ENSRNOT00000111744.1
      Conserved Domains (1) summary
      pfam15086
      Location:5 → 71
      UPF0542; Uncharacterized protein family UPF0542

    2. NM_001277210.2 → NP_001264139.2  small integral membrane protein 15 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) includes an alternate 3' exon structure, compared to variant 1, resulting in a novel 3' coding region and shorter 3' UTR. It encodes isoform 2 which is of the same size but has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A0A0G2JWM3
      Related
      ENSRNOP00000069935.1, ENSRNOT00000083786.2
      Conserved Domains (1) summary
      pfam15086
      Location:5 → 69
      UPF0542; Uncharacterized protein family UPF0542

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      41261710..41266870
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063281080.1 → XP_063137150.1  small integral membrane protein 15 isoform X1

      UniProtKB/TrEMBL
      A6I5J6, D4A573
    Nucleotide Protein Strain
    Heading Accession and Version

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