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    Scfd2 sec1 family domain containing 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498353, updated on 5-Mar-2024

    Summary

    Official Symbol
    Scfd2provided by RGD
    Official Full Name
    sec1 family domain containing 2provided by RGD
    Primary source
    RGD:1562708
    See related
    Ensembl:ENSRNOG00000026828 AllianceGenome:RGD:1562708
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable syntaxin binding activity. Predicted to be involved in intracellular protein transport and vesicle docking involved in exocytosis. Predicted to be active in plasma membrane and secretory granule. Orthologous to human SCFD2 (sec1 family domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Adrenal (RPKM 105.4), Liver (RPKM 86.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Scfd2 in Genome Data Viewer
    Location:
    14p11
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (34037392..34369423)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (33683348..34008232)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (36216002..36543661)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481839 Neighboring gene ligand of numb-protein X 1 Neighboring gene factor interacting with PAPOLA and CPSF1 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC134481840 Neighboring gene uncharacterized LOC102554412 Neighboring gene RAS-like family 11 member B

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    sec1 family domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017499.1NP_001017499.1  sec1 family domain-containing protein 2

      See identical proteins and their annotated locations for NP_001017499.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085889
      UniProtKB/TrEMBL
      A0A8I6A025, Q5U2R9
      Related
      ENSRNOP00000037023.3, ENSRNOT00000038506.4
      Conserved Domains (1) summary
      cl15415
      Location:625665
      Sec1; Sec1 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      34037392..34369423
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_010057401.1 RNA Sequence