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    Cyp4f17 cytochrome P450, family 4, subfamily f, polypeptide 17 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500801, updated on 6-Jun-2024

    Summary

    Official Symbol
    Cyp4f17provided by RGD
    Official Full Name
    cytochrome P450, family 4, subfamily f, polypeptide 17provided by RGD
    Primary source
    RGD:1561655
    See related
    Ensembl:ENSRNOG00000029478 AllianceGenome:RGD:1561655
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1561655
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 27.3), Adrenal (RPKM 25.0) and 9 other tissues See more
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    Genomic context

    See Cyp4f17 in Genome Data Viewer
    Location:
    7q11
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (12169366..12186731)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (11518985..11536208)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (14527797..14545775) , (14550167..14551959)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene peptidoglycan recognition protein 2 Neighboring gene uncharacterized LOC134479822 Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 39 Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 5 Neighboring gene cytochrome P450, family 4, subfamily f, polypeptide 37

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    cytochrome P450, family 4, subfamily f, polypeptide 17

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191986.1NP_001178915.1  cytochrome P450, family 4, subfamily f, polypeptide 17

      See identical proteins and their annotated locations for NP_001178915.1

      Status: INFERRED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/TrEMBL
      A0A8J8Y394, D4AB65
      Conserved Domains (1) summary
      pfam00067
      Location:52514
      p450; Cytochrome P450

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      12169366..12186731
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063264097.1XP_063120167.1  cytochrome P450, family 4, subfamily f, polypeptide 17 isoform X2

      UniProtKB/TrEMBL
      A0A8J8Y394
    2. XM_006241085.5XP_006241147.1  cytochrome P450, family 4, subfamily f, polypeptide 17 isoform X1

      See identical proteins and their annotated locations for XP_006241147.1

      UniProtKB/TrEMBL
      A0A8J8Y394, D4AB65
      Related
      ENSRNOP00000057034.2
      Conserved Domains (1) summary
      pfam00067
      Location:52514
      p450; Cytochrome P450