IRT2 iron regulated transporter 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Gene symbol: IRT2
Gene description: iron regulated transporter 2
Primary source: Araport:AT4G19680
Locus tag: AT4G19680
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATIRT2; iron regulated transporter 2; IRON REGULATED TRANSPORTER 2; T16H5.40; T16H5_40
Summary: encodes an iron transporter whose expression is induced by iron and zinc deficiency. Gene is specifically expressed in the external cell layers of the root subapical zone.
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Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

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NM_001036593.2

NM_118088.4

Function	Evidence Code	Pubs
enables iron ion transmembrane transporter activity	IGI Inferred from Genetic Interaction more info	PubMed
enables iron ion transmembrane transporter activity	TAS Traceable Author Statement more info	PubMed
enables zinc ion transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables zinc ion transmembrane transporter activity	TAS Traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within iron ion transport	TAS Traceable Author Statement more info	PubMed
involved_in zinc ion transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within zinc ion transport	TAS Traceable Author Statement more info	PubMed

NP_001031670.1

iron regulated transporter 2 (IRT2); FUNCTIONS IN: zinc ion transmembrane transporter activity, iron ion transmembrane transporter activity; INVOLVED IN: zinc ion transport, cellular response to iron ion starvation, iron ion transport; LOCATED IN: endomembrane system, integral to membrane, membrane; EXPRESSED IN: root epidermis; CONTAINS InterPro DOMAIN/s: Zinc/iron permease, fungal/plant (InterPro:IPR004698), Zinc/iron permease (InterPro:IPR003689); BEST Arabidopsis thaliana protein match is: iron-regulated transporter 1 (TAIR:AT4G19690.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NP_193703.2

iron regulated transporter 2 (IRT2); FUNCTIONS IN: zinc ion transmembrane transporter activity, iron ion transmembrane transporter activity; INVOLVED IN: zinc ion transport, cellular response to iron ion starvation, iron ion transport; LOCATED IN: endomembrane system, integral to membrane, membrane; EXPRESSED IN: root epidermis; CONTAINS InterPro DOMAIN/s: Zinc/iron permease, fungal/plant (InterPro:IPR004698), Zinc/iron permease (InterPro:IPR003689); BEST Arabidopsis thaliana protein match is: iron-regulated transporter 1 (TAIR:AT4G19690.2); Has 1381 Blast hits to 1243 proteins in 190 species: Archae - 0; Bacteria - 10; Metazoa - 183; Fungi - 601; Plants - 483; Viruses - 0; Other Eukaryotes - 104 (source: NCBI BLink).