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    Ofa oncofetal antigen [ Mus musculus (house mouse) ]

    Gene ID: 18290, updated on 7-Sep-2023

    Summary

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    Official Symbol
    Ofaprovided by MGI
    Official Full Name
    oncofetal antigenprovided by MGI
    Primary source
    MGI:MGI:99880
    See related
    AllianceGenome:MGI:99880
    Gene type
    protein coding
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    59kDa
    Summary
    Located in cell surface. [provided by Alliance of Genome Resources, Apr 2022]
    Annotation information
    not in current annotation release
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    Bibliography

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    Related articles in PubMed

    1. Identification of HLA-A*0201-presented T cell epitopes derived from the oncofetal antigen-immature laminin receptor protein in patients with hematological malignancies. Siegel S, et al. J Immunol, 2006 Jun 1. PMID 16709854
    2. Identification of oncofetal antigen/immature laminin receptor protein epitopes that activate BALB/c mouse OFA/iLRP-specific effector and regulatory T cell clones. Rohrer JW, et al. J Immunol, 2006 Mar 1. PMID 16493041
    3. Identification of partial complementary DNA clones encoding a 59-kd protein with characteristics of a unique oncofetal antigen. Rashid HU, et al. J Natl Cancer Inst, 1994 Apr 6. PMID 8133535

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These experiments identify the epitopes recognized by CD8 T cell clones specific for OFA/immature laminin receptor protein (ILRP) and demonstrate their ability to limit tumor growth and metastasis in vivo.
      Title: Identification of oncofetal antigen/immature laminin receptor protein epitopes that activate BALB/c mouse OFA/iLRP-specific effector and regulatory T cell clones.
    2. OFA-immature laminin receptor (iLR)-specific cytotoxic T-lymphocytes (CTLs) can play a role in controlling OFA-iLR-expressing tumor cells.
      Title: Identification of HLA-A*0201-presented T cell epitopes derived from the oncofetal antigen-immature laminin receptor protein in patients with hematological malignancies.
    Submit: New GeneRIF Correction

    General gene information

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    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cell surface IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    oncofetal antigen
    Names
    oncofetal antigen, 59 kDa
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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