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    NRCAM neuronal cell adhesion molecule [ Bos taurus (cattle) ]

    Gene ID: 534500, updated on 3-Apr-2024

    Summary

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    Official Symbol
    NRCAMprovided by VGNC
    Official Full Name
    neuronal cell adhesion moleculeprovided by VGNC
    Primary source
    VGNC:VGNC:32257
    See related
    BGD:BT11439; Ensembl:ENSBTAG00000006732
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See NRCAM in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (49242859..49563407, complement)

    Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene laminin subunit beta 1 Neighboring gene microRNA mir-2418 Neighboring gene uncharacterized LOC132345089 Neighboring gene uncharacterized LOC112446376 Neighboring gene patatin like phospholipase domain containing 8

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cell-cell adhesion mediator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in brain development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neuronal cell adhesion molecule
    Names
    neuronal cell adhesion protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206562.1 → NP_001193491.1  neuronal cell adhesion molecule

      See identical proteins and their annotated locations for NP_001193491.1

      Status: VALIDATED

      Source sequence(s)
      AAFC03072056, AAFC03091706
      UniProtKB/TrEMBL
      A0A3Q1N110
      Related
      ENSBTAP00000062561.2, ENSBTAT00000068765.2
      Conserved Domains (8) summary
      cd05868
      Location:357 → 431
      Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
      smart00408
      Location:450 → 513
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:53 → 135
      IG_like; Immunoglobulin like
      cd00063
      Location:628 → 718
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:528 → 614
      I-set; Immunoglobulin I-set domain
      pfam00041
      Location:731 → 813
      fn3; Fibronectin type III domain
      pfam13882
      Location:1067 → 1156
      Bravo_FIGEY; Bravo-like intracellular region
      cl11960
      Location:64 → 140
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      49242859..49563407 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024990762.2 → XP_024846530.1  neuronal cell adhesion molecule isoform X19

      UniProtKB/TrEMBL
      A0A3Q1LP71
      Conserved Domains (7) summary
      cd05868
      Location:376 → 450
      Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
      cd00063
      Location:647 → 737
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:953 → 1037
      fn3; Fibronectin type III domain
      pfam13882
      Location:1189 → 1278
      Bravo_FIGEY; Bravo-like intracellular region
      pfam13927
      Location:453 → 529
      Ig_3; Immunoglobulin domain
      cl11960
      Location:64 → 140
      Ig; Immunoglobulin domain
      cl28434
      Location:547 → 633
      I-set; Immunoglobulin I-set domain

    2. XM_059885646.1 → XP_059741629.1  neuronal cell adhesion molecule isoform X5

    3. XM_010804207.4 → XP_010802509.2  neuronal cell adhesion molecule isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LP71
      Conserved Domains (7) summary
      cd05868
      Location:376 → 450
      Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
      cd00063
      Location:647 → 737
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:953 → 1037
      fn3; Fibronectin type III domain
      pfam13882
      Location:1101 → 1190
      Bravo_FIGEY; Bravo-like intracellular region
      pfam13927
      Location:453 → 529
      Ig_3; Immunoglobulin domain
      cl11960
      Location:64 → 140
      Ig; Immunoglobulin domain
      cl28434
      Location:547 → 633
      I-set; Immunoglobulin I-set domain

    4. XM_059885653.1 → XP_059741636.1  neuronal cell adhesion molecule isoform X18

      Related
      ENSBTAP00000068074.2, ENSBTAT00000066362.2

    5. XM_010804215.4 → XP_010802517.2  neuronal cell adhesion molecule isoform X14

      UniProtKB/TrEMBL
      A0A3Q1M3L7
      Related
      ENSBTAP00000058702.2, ENSBTAT00000073623.2
      Conserved Domains (7) summary
      cd05868
      Location:370 → 444
      Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
      cd00063
      Location:631 → 721
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:937 → 1021
      fn3; Fibronectin type III domain
      pfam13882
      Location:1073 → 1162
      Bravo_FIGEY; Bravo-like intracellular region
      pfam13927
      Location:447 → 523
      Ig_3; Immunoglobulin domain
      cl11960
      Location:58 → 134
      Ig; Immunoglobulin domain
      cl28434
      Location:541 → 627
      I-set; Immunoglobulin I-set domain

    6. XM_059885647.1 → XP_059741630.1  neuronal cell adhesion molecule isoform X8

      Related
      ENSBTAP00000068113.2, ENSBTAT00000080861.2

    7. XM_059885645.1 → XP_059741628.1  neuronal cell adhesion molecule isoform X4

      UniProtKB/TrEMBL
      A0A3Q1MBI4

    8. XM_059885644.1 → XP_059741627.1  neuronal cell adhesion molecule isoform X3

    9. XM_005205430.5 → XP_005205487.2  neuronal cell adhesion molecule isoform X17

      UniProtKB/TrEMBL
      A0A3Q1N110
      Conserved Domains (7) summary
      cd05868
      Location:357 → 431
      Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
      cd00063
      Location:628 → 718
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:934 → 1018
      fn3; Fibronectin type III domain
      pfam13882
      Location:1067 → 1156
      Bravo_FIGEY; Bravo-like intracellular region
      pfam13927
      Location:434 → 510
      Ig_3; Immunoglobulin domain
      cl11960
      Location:64 → 140
      Ig; Immunoglobulin domain
      cl28434
      Location:528 → 614
      I-set; Immunoglobulin I-set domain

    10. XM_005205427.5 → XP_005205484.2  neuronal cell adhesion molecule isoform X11

      UniProtKB/TrEMBL
      A0A3Q1N110
      Conserved Domains (7) summary
      cd05868
      Location:357 → 431
      Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
      cd00063
      Location:628 → 718
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:934 → 1018
      fn3; Fibronectin type III domain
      pfam13882
      Location:1079 → 1168
      Bravo_FIGEY; Bravo-like intracellular region
      pfam13927
      Location:434 → 510
      Ig_3; Immunoglobulin domain
      cl11960
      Location:64 → 140
      Ig; Immunoglobulin domain
      cl28434
      Location:528 → 614
      I-set; Immunoglobulin I-set domain

    11. XM_059885652.1 → XP_059741635.1  neuronal cell adhesion molecule isoform X16

    12. XM_059885648.1 → XP_059741631.1  neuronal cell adhesion molecule isoform X9

    13. XM_024990760.2 → XP_024846528.1  neuronal cell adhesion molecule isoform X13

      UniProtKB/TrEMBL
      A0A3Q1M3L7
      Conserved Domains (7) summary
      cd05868
      Location:376 → 450
      Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
      cd00063
      Location:637 → 727
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:943 → 1027
      fn3; Fibronectin type III domain
      pfam13882
      Location:1076 → 1165
      Bravo_FIGEY; Bravo-like intracellular region
      pfam13927
      Location:453 → 529
      Ig_3; Immunoglobulin domain
      cl11960
      Location:64 → 140
      Ig; Immunoglobulin domain
      cl28434
      Location:547 → 633
      I-set; Immunoglobulin I-set domain

    14. XM_059885651.1 → XP_059741634.1  neuronal cell adhesion molecule isoform X12

    15. XM_010804212.4 → XP_010802514.2  neuronal cell adhesion molecule isoform X7

      UniProtKB/TrEMBL
      A0A3Q1M3L7
      Conserved Domains (7) summary
      cd05868
      Location:376 → 450
      Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
      cd00063
      Location:647 → 737
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:953 → 1037
      fn3; Fibronectin type III domain
      pfam13882
      Location:1086 → 1175
      Bravo_FIGEY; Bravo-like intracellular region
      pfam13927
      Location:453 → 529
      Ig_3; Immunoglobulin domain
      cl11960
      Location:64 → 140
      Ig; Immunoglobulin domain
      cl28434
      Location:547 → 633
      I-set; Immunoglobulin I-set domain

    16. XM_005205426.5 → XP_005205483.2  neuronal cell adhesion molecule isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LP71
      Conserved Domains (7) summary
      cd05868
      Location:376 → 450
      Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
      cd00063
      Location:647 → 737
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:953 → 1037
      fn3; Fibronectin type III domain
      pfam13882
      Location:1098 → 1187
      Bravo_FIGEY; Bravo-like intracellular region
      pfam13927
      Location:453 → 529
      Ig_3; Immunoglobulin domain
      cl11960
      Location:64 → 140
      Ig; Immunoglobulin domain
      cl28434
      Location:547 → 633
      I-set; Immunoglobulin I-set domain

    17. XM_005205429.5 → XP_005205486.2  neuronal cell adhesion molecule isoform X15

      UniProtKB/TrEMBL
      A0A3Q1M3L7
      Related
      ENSBTAP00000008864.7, ENSBTAT00000008864.7
      Conserved Domains (7) summary
      cd05868
      Location:370 → 444
      Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
      cd00063
      Location:631 → 721
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:937 → 1021
      fn3; Fibronectin type III domain
      pfam13882
      Location:1070 → 1159
      Bravo_FIGEY; Bravo-like intracellular region
      pfam13927
      Location:447 → 523
      Ig_3; Immunoglobulin domain
      cl11960
      Location:58 → 134
      Ig; Immunoglobulin domain
      cl28434
      Location:541 → 627
      I-set; Immunoglobulin I-set domain

    18. XM_059885649.1 → XP_059741632.1  neuronal cell adhesion molecule isoform X10

      UniProtKB/TrEMBL
      E1BLM2

    19. XM_024990759.2 → XP_024846527.1  neuronal cell adhesion molecule isoform X6

      UniProtKB/TrEMBL
      A0A3Q1M3L7
      Conserved Domains (7) summary
      cd05868
      Location:376 → 450
      Ig4_NrCAM; Fourth immunoglobulin (Ig)-like domain of NrCAM (NgCAM-related cell adhesion molecule)
      cd00063
      Location:647 → 737
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam00041
      Location:953 → 1037
      fn3; Fibronectin type III domain
      pfam13882
      Location:1089 → 1178
      Bravo_FIGEY; Bravo-like intracellular region
      pfam13927
      Location:453 → 529
      Ig_3; Immunoglobulin domain
      cl11960
      Location:64 → 140
      Ig; Immunoglobulin domain
      cl28434
      Location:547 → 633
      I-set; Immunoglobulin I-set domain
    Nucleotide Protein Strain
    Heading Accession and Version

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