CASP6 caspase 6 [Bos taurus (cattle)] - Gene

Summary

Official Symbol: CASP6provided by VGNC
Official Full Name: caspase 6provided by VGNC
Primary source: VGNC:VGNC:26782
See related: BGD:BT27334; Ensembl:ENSBTAG00000012537
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	6	NC_037333.1 (15694142..15714982)

Chromosome 6 - NC_037333.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

MARC_31396-31397:1046885089:1 (e-PCR)
- UniSTS:466580

MARC_31398-31399:1046885427:1 (e-PCR)
- UniSTS:466581

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cysteine-type endopeptidase activity involved in execution phase of apoptosis	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: caspase-6

Names: CASP-6; caspase 6, apoptosis-related cysteine peptidase

NP_001030496.1

EC 3.4.22.59

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001035419.2 → NP_001030496.1 caspase-6

See identical proteins and their annotated locations for NP_001030496.1

Status: PROVISIONAL

Source sequence(s)

BC102309

UniProtKB/Swiss-Prot

Q3T0P5

UniProtKB/TrEMBL

A0AAA9SFJ8

Related

ENSBTAP00000016642.5, ENSBTAT00000016642.6

Conserved Domains (1) summary

cd00032
Location:37 → 288

CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues; Cysteine-dependent aspartate-directed proteases that mediate programmed cell death (apoptosis). Caspases are synthesized as inactive zymogens and activated by proteolysis of the peptide ...