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    ERLIN1 ER lipid raft associated 1 [ Bos taurus (cattle) ]

    Gene ID: 617074, updated on 6-Jun-2024

    Summary

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    Official Symbol
    ERLIN1provided by VGNC
    Official Full Name
    ER lipid raft associated 1provided by VGNC
    Primary source
    VGNC:VGNC:28588
    See related
    BGD:BT19665; Ensembl:ENSBTAG00000007588
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ERLIN1 in Genome Data Viewer
    Location:
    chromosome: 26
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 26 NC_037353.1 (21052721..21094493, complement)

    Chromosome 26 - NC_037353.1Genomic Context describing neighboring genes Neighboring gene carboxypeptidase N subunit 1 Neighboring gene U6 spliceosomal RNA Neighboring gene cytochrome P450 family 2 subfamily C member 23 Neighboring gene component of inhibitor of nuclear factor kappa B kinase complex Neighboring gene small nucleolar RNA SNORA12 Neighboring gene CWF19 like cell cycle control factor 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037353.1 Chromosome 26 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cholesterol binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in SREBP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    erlin-1
    Names
    SPFH domain family, member 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164032.3 → NP_001157504.1  erlin-1

      See identical proteins and their annotated locations for NP_001157504.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000026
      UniProtKB/TrEMBL
      A0A3Q1MZY2, G3N0U8
      Related
      ENSBTAP00000055467.1, ENSBTAT00000064463.2
      Conserved Domains (1) summary
      cd03406
      Location:23 → 310
      SPFH_like_u3; Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037353.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      21052721..21094493 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005225631.5 → XP_005225688.1  erlin-1 isoform X1

      See identical proteins and their annotated locations for XP_005225688.1

      UniProtKB/TrEMBL
      A0A3Q1MZY2, G3N0U8
      Related
      ENSBTAP00000061866.1, ENSBTAT00000070809.2
      Conserved Domains (1) summary
      cd03406
      Location:23 → 310
      SPFH_like_u3; Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    2. XM_059881950.1 → XP_059737933.1  erlin-1 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LSF1, A0A3Q1MZY2
      Related
      ENSBTAP00000060169.1, ENSBTAT00000086029.2

    3. XM_024985825.2 → XP_024841593.1  erlin-1 isoform X5

      Conserved Domains (1) summary
      cl19107
      Location:1 → 150
      SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    4. XM_024985824.2 → XP_024841592.2  erlin-1 isoform X4

    5. XM_024985823.1 → XP_024841591.1  erlin-1 isoform X3

      Conserved Domains (1) summary
      cl19107
      Location:1 → 226
      SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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