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    ASAH1 N-acylsphingosine amidohydrolase 1 [ Bos taurus (cattle) ]

    Gene ID: 510620, updated on 6-Jun-2024

    Summary

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    Official Symbol
    ASAH1provided by VGNC
    Official Full Name
    N-acylsphingosine amidohydrolase 1provided by VGNC
    Primary source
    VGNC:VGNC:26183
    See related
    BGD:BT23704; Ensembl:ENSBTAG00000011257
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ASAH1 in Genome Data Viewer
    Location:
    chromosome: 27
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 27 NC_037354.1 (19211654..19243281)

    Chromosome 27 - NC_037354.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107131907 Neighboring gene small nucleolar RNA U2-30 Neighboring gene calcyclin-binding protein-like Neighboring gene FSHD region gene 1 Neighboring gene pericentriolar material 1 Neighboring gene microRNA mir-2398 Neighboring gene fibrinogen like 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037354.1 Chromosome 27 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC140781

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables N-acylsphingosine amidohydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables fatty acid amide hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fatty acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    acid ceramidase
    Names
    AC
    ACDase
    N-acylethanolamine hydrolase ASAH1
    acid CDase
    acylsphingosine deacylase
    NP_001068927.1
    XP_005226024.1
    XP_024841992.1
    XP_059738167.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075459.2 → NP_001068927.1  acid ceramidase precursor

      See identical proteins and their annotated locations for NP_001068927.1

      Status: PROVISIONAL

      Source sequence(s)
      BC118455
      UniProtKB/Swiss-Prot
      Q17QB3
      UniProtKB/TrEMBL
      A0AAA9S7S0
      Related
      ENSBTAP00000014960.3, ENSBTAT00000014960.4
      Conserved Domains (2) summary
      cd01903
      Location:134 → 379
      Ntn_AC_NAAA; AC_NAAA This conserved domain includes two closely related proteins, acid ceramidase (AC, also known as N-acylsphingosine amidohydrolase), and N-acylethanolamine-hydrolyzing acid amidase (NAAA). AC catalyzes the hydrolysis of ceramide to sphingosine and ...
      pfam15508
      Location:45 → 139
      NAAA-beta; beta subunit of N-acylethanolamine-hydrolyzing acid amidase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037354.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      19211654..19243281
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005225967.5 → XP_005226024.1  acid ceramidase isoform X1

      See identical proteins and their annotated locations for XP_005226024.1

      UniProtKB/TrEMBL
      A0AAA9SDL7
      Conserved Domains (2) summary
      cd01903
      Location:69 → 314
      Ntn_AC_NAAA; AC_NAAA This conserved domain includes two closely related proteins, acid ceramidase (AC, also known as N-acylsphingosine amidohydrolase), and N-acylethanolamine-hydrolyzing acid amidase (NAAA). AC catalyzes the hydrolysis of ceramide to sphingosine and ...
      pfam15508
      Location:4 → 43
      NAAA-beta; beta subunit of N-acylethanolamine-hydrolyzing acid amidase

    2. XM_024986224.2 → XP_024841992.1  acid ceramidase isoform X1

      UniProtKB/TrEMBL
      A0AAA9SDL7
      Conserved Domains (2) summary
      cd01903
      Location:69 → 314
      Ntn_AC_NAAA; AC_NAAA This conserved domain includes two closely related proteins, acid ceramidase (AC, also known as N-acylsphingosine amidohydrolase), and N-acylethanolamine-hydrolyzing acid amidase (NAAA). AC catalyzes the hydrolysis of ceramide to sphingosine and ...
      pfam15508
      Location:4 → 43
      NAAA-beta; beta subunit of N-acylethanolamine-hydrolyzing acid amidase

    3. XM_059882184.1 → XP_059738167.1  acid ceramidase isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q17QB3.3 GenPept UniProtKB/Swiss-Prot:Q17QB3

    Gene LinkOut

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