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    Ypel5 yippee-like 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298792, updated on 3-Apr-2024

    Summary

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    Symbol
    Ypel5provided by RGD
    Full Name
    yippee-like 5provided by RGD
    Primary source
    RGD:1309657
    See related
    Ensembl:ENSRNOG00000026742 AllianceGenome:RGD:1309657
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable metal ion binding activity. Predicted to be part of ubiquitin ligase complex. Orthologous to human YPEL5 (yippee like 5). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Spleen (RPKM 469.9), Brain (RPKM 331.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ypel5 in Genome Data Viewer
    Location:
    6q14
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (28408079..28423536, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (22656284..22671741, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (24069351..24084758)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108351184 Neighboring gene LBH regulator of WNT signaling pathway Neighboring gene uncharacterized LOC103692567 Neighboring gene uncharacterized LOC108351183 Neighboring gene ALK receptor tyrosine kinase Neighboring gene stratifin like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation. Lampert F, et al. Elife, 2018 Jun 18. PMID 29911972, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    part_of ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein yippee-like 5
    NP_001030298.1
    XP_008762730.1
    XP_008762731.1
    XP_008762732.1
    XP_038967832.1
    XP_038967833.1
    XP_038967835.1
    XP_063117688.1
    XP_063117689.1
    XP_063117690.1
    XP_063117692.1
    XP_063117693.1
    XP_063117694.1
    XP_063117695.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035221.1 → NP_001030298.1  protein yippee-like 5

      See identical proteins and their annotated locations for NP_001030298.1

      Status: PROVISIONAL

      Source sequence(s)
      BC105836, CB584328
      UniProtKB/TrEMBL
      A6HA10, D4A4Q3
      Related
      ENSRNOP00000038910.4, ENSRNOT00000035362.5
      Conserved Domains (1) summary
      cl13152
      Location:15 → 107
      RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      28408079..28423536 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039111905.2 → XP_038967833.1  protein yippee-like 5 isoform X1

      UniProtKB/TrEMBL
      A6HA10, D4A4Q3
      Conserved Domains (1) summary
      cl13152
      Location:15 → 107
      RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

    2. XM_039111907.2 → XP_038967835.1  protein yippee-like 5 isoform X1

      UniProtKB/TrEMBL
      A6HA10, D4A4Q3
      Conserved Domains (1) summary
      cl13152
      Location:15 → 107
      RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

    3. XM_008764508.3 → XP_008762730.1  protein yippee-like 5 isoform X1

      See identical proteins and their annotated locations for XP_008762730.1

      UniProtKB/TrEMBL
      A6HA10, D4A4Q3
      Conserved Domains (1) summary
      cl13152
      Location:15 → 107
      RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

    4. XM_063261622.1 → XP_063117692.1  protein yippee-like 5 isoform X1

      UniProtKB/TrEMBL
      A6HA10, D4A4Q3

    5. XM_063261625.1 → XP_063117695.1  protein yippee-like 5 isoform X1

      UniProtKB/TrEMBL
      A6HA10, D4A4Q3

    6. XM_008764510.4 → XP_008762732.1  protein yippee-like 5 isoform X1

      See identical proteins and their annotated locations for XP_008762732.1

      UniProtKB/TrEMBL
      A6HA10, D4A4Q3
      Conserved Domains (1) summary
      cl13152
      Location:15 → 107
      RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

    7. XM_008764509.4 → XP_008762731.1  protein yippee-like 5 isoform X1

      See identical proteins and their annotated locations for XP_008762731.1

      UniProtKB/TrEMBL
      A6HA10, D4A4Q3
      Conserved Domains (1) summary
      cl13152
      Location:15 → 107
      RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

    8. XM_063261620.1 → XP_063117690.1  protein yippee-like 5 isoform X1

      UniProtKB/TrEMBL
      A6HA10, D4A4Q3

    9. XM_063261618.1 → XP_063117688.1  protein yippee-like 5 isoform X1

      UniProtKB/TrEMBL
      A6HA10, D4A4Q3

    10. XM_063261623.1 → XP_063117693.1  protein yippee-like 5 isoform X1

      UniProtKB/TrEMBL
      A6HA10, D4A4Q3

    11. XM_039111904.2 → XP_038967832.1  protein yippee-like 5 isoform X1

      UniProtKB/TrEMBL
      A6HA10, D4A4Q3
      Conserved Domains (1) summary
      cl13152
      Location:15 → 107
      RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

    12. XM_063261624.1 → XP_063117694.1  protein yippee-like 5 isoform X1

      UniProtKB/TrEMBL
      A6HA10, D4A4Q3

    13. XM_063261619.1 → XP_063117689.1  protein yippee-like 5 isoform X1

      UniProtKB/TrEMBL
      A6HA10, D4A4Q3

    RNA

    1. XR_005505462.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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