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    Rpp25l ribonuclease P/MRP subunit p25 like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298002, updated on 5-Mar-2024

    Summary

    Official Symbol
    Rpp25lprovided by RGD
    Official Full Name
    ribonuclease P/MRP subunit p25 likeprovided by RGD
    Primary source
    RGD:1306576
    See related
    Ensembl:ENSRNOG00000064027 AllianceGenome:RGD:1306576
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306576
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in tRNA 5'-leader removal. Predicted to be part of ribonuclease MRP complex. Orthologous to human RPP25L (ribonuclease P/MRP subunit p25 like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Muscle (RPKM 50.3), Thymus (RPKM 47.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Rpp25l in Genome Data Viewer
    Location:
    5q22
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (61674299..61675844, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (56878420..56879956, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (58096037..58097577, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene energy homeostasis associated Neighboring gene ciliary neurotrophic factor receptor Neighboring gene dynactin subunit 3 Neighboring gene AT-rich interaction domain 3C

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in tRNA 5'-leader removal IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonuclease MRP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ribonuclease P protein subunit p25-like protein
    Names
    ribonuclease P/MRP 25 subunit-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106648.2NP_001100118.1  ribonuclease P protein subunit p25-like protein

      See identical proteins and their annotated locations for NP_001100118.1

      Status: PROVISIONAL

      Source sequence(s)
      BC158601
      UniProtKB/TrEMBL
      A0A8I5ZQ64, A6IIW5, B0BMX6
      Related
      ENSRNOP00000080493.1, ENSRNOT00000105681.1
      Conserved Domains (1) summary
      pfam01918
      Location:2789
      Alba

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      61674299..61675844 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006238032.4XP_006238094.1  ribonuclease P protein subunit p25-like protein isoform X1

      See identical proteins and their annotated locations for XP_006238094.1

      UniProtKB/TrEMBL
      A0A8I5ZQ64, A6IIW5, B0BMX6
      Conserved Domains (1) summary
      pfam01918
      Location:2789
      Alba
    2. XM_006238031.4XP_006238093.1  ribonuclease P protein subunit p25-like protein isoform X1

      See identical proteins and their annotated locations for XP_006238093.1

      UniProtKB/TrEMBL
      A0A8I5ZQ64, A6IIW5, B0BMX6
      Conserved Domains (1) summary
      pfam01918
      Location:2789
      Alba