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    Shisa4 shisa family member 4 [ Mus musculus (house mouse) ]

    Gene ID: 77552, updated on 21-Apr-2024

    Summary

    Official Symbol
    Shisa4provided by MGI
    Official Full Name
    shisa family member 4provided by MGI
    Primary source
    MGI:MGI:1924802
    See related
    Ensembl:ENSMUSG00000041889 AllianceGenome:MGI:1924802
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tmem58; mShisa4; 9330132O05Rik
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including eye; gut; limb; male reproductive gland or organ; and nervous system. Orthologous to human SHISA4 (shisa family member 4). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in cortex adult (RPKM 47.1), frontal lobe adult (RPKM 41.4) and 18 other tissues See more
    Orthologs
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    Genomic context

    Location:
    1 E4; 1 58.58 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (135298578..135302812, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (135371057..135375298, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_02362 Neighboring gene predicted gene, 41956 Neighboring gene leiomodin 1 (smooth muscle) Neighboring gene STARR-seq mESC enhancer starr_02364 Neighboring gene STARR-seq mESC enhancer starr_02365 Neighboring gene importin 9 Neighboring gene STARR-positive B cell enhancer ABC_E10038 Neighboring gene neuron navigator 1 Neighboring gene microRNA 1231

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General protein information

    Preferred Names
    protein shisa-4
    Names
    shisa homolog 4
    transmembrane protein 58

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175259.5NP_780468.1  protein shisa-4 precursor

      See identical proteins and their annotated locations for NP_780468.1

      Status: VALIDATED

      Source sequence(s)
      AC016814
      Consensus CDS
      CCDS15319.1
      UniProtKB/Swiss-Prot
      Q8CA71
      Related
      ENSMUSP00000046033.4, ENSMUST00000041240.4
      Conserved Domains (1) summary
      pfam13908
      Location:29178
      Shisa; Wnt and FGF inhibitory regulator

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      135298578..135302812 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)