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    ELMO1 engulfment and cell motility 1 [ Bos taurus (cattle) ]

    Gene ID: 509821, updated on 5-Mar-2024

    Summary

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    Official Symbol
    ELMO1provided by VGNC
    Official Full Name
    engulfment and cell motility 1provided by VGNC
    Primary source
    VGNC:VGNC:28438
    See related
    BGD:BT22540; Ensembl:ENSBTAG00000003490
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ELMO1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 4 NC_037331.1 (59868012..60450511)

    Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132345100 Neighboring gene uncharacterized LOC112446385 Neighboring gene uncharacterized LOC132345101 Neighboring gene uncharacterized LOC104972076 Neighboring gene small ribosomal subunit protein eS7-like Neighboring gene acyloxyacyl hydrolase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC139838

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in actin filament organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell motility IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of guanyl-nucleotide exchange factor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    engulfment and cell motility protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024505.3 → NP_001019676.1  engulfment and cell motility protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001019676.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) represents an alternate 5'UTR, resulting in use of a downstream in-frame start codon as compared to variant 1. Isoform 2 is significantly shorter than isoform 1.
      Source sequence(s)
      BC149493, EE239012, NKLS02000004
      UniProtKB/TrEMBL
      Q5EAA6
      Conserved Domains (1) summary
      cd13359
      Location:66 → 195
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain

    2. NM_001113227.2 → NP_001106698.1  engulfment and cell motility protein 1 isoform 1

      See identical proteins and their annotated locations for NP_001106698.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      BC149493, EV677253, NKLS02000004
      UniProtKB/TrEMBL
      F1MQH0
      Conserved Domains (3) summary
      cd13359
      Location:546 → 675
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:303 → 481
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:116 → 279
      DUF3361; Domain of unknown function (DUF3361)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037331.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      59868012..60450511
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015469368.3 → XP_015324854.1  engulfment and cell motility protein 1 isoform X1

      UniProtKB/TrEMBL
      F1MQH0
      Conserved Domains (3) summary
      cd13359
      Location:546 → 675
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:303 → 481
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:116 → 279
      DUF3361; Domain of unknown function (DUF3361)

    2. XM_015469370.3 → XP_015324856.1  engulfment and cell motility protein 1 isoform X1

      UniProtKB/TrEMBL
      F1MQH0
      Related
      ENSBTAP00000038993.4, ENSBTAT00000039193.6
      Conserved Domains (3) summary
      cd13359
      Location:546 → 675
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:303 → 481
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:116 → 279
      DUF3361; Domain of unknown function (DUF3361)

    3. XM_059885500.1 → XP_059741483.1  engulfment and cell motility protein 1 isoform X1

      UniProtKB/TrEMBL
      F1MQH0

    4. XM_015469366.3 → XP_015324852.1  engulfment and cell motility protein 1 isoform X1

      UniProtKB/TrEMBL
      F1MQH0
      Conserved Domains (3) summary
      cd13359
      Location:546 → 675
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:303 → 481
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:116 → 279
      DUF3361; Domain of unknown function (DUF3361)

    5. XM_005205454.4 → XP_005205511.1  engulfment and cell motility protein 1 isoform X1

      See identical proteins and their annotated locations for XP_005205511.1

      UniProtKB/TrEMBL
      F1MQH0
      Conserved Domains (3) summary
      cd13359
      Location:546 → 675
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:303 → 481
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:116 → 279
      DUF3361; Domain of unknown function (DUF3361)

    6. XM_015469371.2 → XP_015324857.1  engulfment and cell motility protein 1 isoform X1

      UniProtKB/TrEMBL
      F1MQH0
      Conserved Domains (3) summary
      cd13359
      Location:546 → 675
      PH_ELMO1_CED-12; Engulfment and cell motility protein 1 pleckstrin homology (PH) domain
      pfam04727
      Location:303 → 481
      ELMO_CED12; ELMO/CED-12 family
      pfam11841
      Location:116 → 279
      DUF3361; Domain of unknown function (DUF3361)
    Nucleotide Protein Strain
    Heading Accession and Version

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