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    NBR1 NBR1 autophagy cargo receptor [ Bos taurus (cattle) ]

    Gene ID: 515032, updated on 6-Jun-2024

    Summary

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    Official Symbol
    NBR1provided by VGNC
    Official Full Name
    NBR1 autophagy cargo receptorprovided by VGNC
    Primary source
    VGNC:VGNC:31896
    See related
    BGD:BT25616; Ensembl:ENSBTAG00000001632
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See NBR1 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (43140304..43169401)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene Rho family GTPase 2 Neighboring gene BRCA1 DNA repair associated Neighboring gene transmembrane protein 106A Neighboring gene coiled-coil domain containing 200

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in macroautophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in phagophore assembly site IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    next to BRCA1 gene 1 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100367.2 → NP_001093837.1  next to BRCA1 gene 1 protein

      See identical proteins and their annotated locations for NP_001093837.1

      Status: PROVISIONAL

      Source sequence(s)
      BC149979
      UniProtKB/TrEMBL
      A6QQS9, F6Q0N3
      Related
      ENSBTAP00000011617.6, ENSBTAT00000011617.6
      Conserved Domains (5) summary
      cd06396
      Location:5 → 85
      PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...
      cd02340
      Location:215 → 259
      ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...
      cd14319
      Location:936 → 974
      UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins
      cd14947
      Location:369 → 479
      NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins
      cl00613
      Location:288 → 335
      ATP-synt_D; ATP synthase subunit D

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      43140304..43169401
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005220724.4 → XP_005220781.1  next to BRCA1 gene 1 protein isoform X1

      See identical proteins and their annotated locations for XP_005220781.1

      UniProtKB/TrEMBL
      A6QQS9, F6Q0N3
      Related
      ENSBTAP00000063640.1, ENSBTAT00000087334.1
      Conserved Domains (5) summary
      cd06396
      Location:5 → 85
      PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...
      cd02340
      Location:215 → 259
      ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...
      cd14319
      Location:936 → 974
      UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins
      cd14947
      Location:369 → 479
      NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins
      cl00613
      Location:288 → 335
      ATP-synt_D; ATP synthase subunit D

    2. XM_059878024.1 → XP_059734007.1  next to BRCA1 gene 1 protein isoform X1

      UniProtKB/TrEMBL
      A6QQS9, F6Q0N3

    3. XM_010816243.4 → XP_010814545.1  next to BRCA1 gene 1 protein isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LVI4, F6Q0N3
      Related
      ENSBTAP00000064643.2, ENSBTAT00000069104.2
      Conserved Domains (5) summary
      cd06396
      Location:5 → 85
      PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...
      cd02340
      Location:189 → 233
      ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...
      cd14319
      Location:910 → 948
      UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins
      cd14947
      Location:343 → 453
      NBR1_like; Functionally uncharacterized domain in neighbor of Brca1 Gene 1 and related proteins
      cl00613
      Location:262 → 309
      ATP-synt_D; ATP synthase subunit D

    4. XM_059878025.1 → XP_059734008.1  next to BRCA1 gene 1 protein isoform X3

      UniProtKB/TrEMBL
      F6Q0N3
    Nucleotide Protein Strain
    Heading Accession and Version

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