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    Slc66a3 solute carrier family 66 member 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298906, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Slc66a3provided by RGD
    Official Full Name
    solute carrier family 66 member 3provided by RGD
    Primary source
    RGD:1306818
    See related
    Ensembl:ENSRNOG00000005126 AllianceGenome:RGD:1306818
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Pqlc3; RGD1306818
    Summary
    Predicted to be integral component of membrane. Orthologous to human SLC66A3 (solute carrier family 66 member 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Lung (RPKM 110.8), Spleen (RPKM 71.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Slc66a3 in Genome Data Viewer
    Location:
    6q16
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (45503541..45515293, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (39774801..39786554, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (42290678..42302451, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene growth regulating estrogen receptor binding 1 Neighboring gene E2F transcription factor 6 Neighboring gene Rho-associated coiled-coil containing protein kinase 2 Neighboring gene uncharacterized LOC134479346 Neighboring gene similar to human chromosome 2 open reading frame 50 Neighboring gene potassium voltage-gated channel modifier subfamily F member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    solute carrier family 66 member 3
    Names
    PQ loop repeat containing 3
    PQ-loop repeat-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034952.1 → NP_001030124.1  solute carrier family 66 member 3 precursor

      See identical proteins and their annotated locations for NP_001030124.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081879, CB556892, CK477351
      UniProtKB/TrEMBL
      A6HAT8, G3V6N5
      Related
      ENSRNOP00000007071.5, ENSRNOT00000007071.7
      Conserved Domains (1) summary
      pfam04193
      Location:5 → 53
      PQ-loop; PQ loop repeat

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      45503541..45515293 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039111949.1 → XP_038967877.1  solute carrier family 66 member 3 isoform X3

      UniProtKB/TrEMBL
      A0A8I5YCE9
      Related
      ENSRNOP00000077550.1, ENSRNOT00000108174.1
      Conserved Domains (1) summary
      pfam04193
      Location:5 → 53
      PQ-loop; PQ loop repeat

    2. XM_008764587.4 → XP_008762809.1  solute carrier family 66 member 3 isoform X2

      UniProtKB/TrEMBL
      A0A8I6A368
      Related
      ENSRNOP00000085412.1
      Conserved Domains (1) summary
      pfam04193
      Location:5 → 53
      PQ-loop; PQ loop repeat

    3. XM_039111947.2 → XP_038967875.1  solute carrier family 66 member 3 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZZ26
      Related
      ENSRNOP00000084445.1
      Conserved Domains (1) summary
      pfam04193
      Location:5 → 53
      PQ-loop; PQ loop repeat
    Nucleotide Protein Strain
    Heading Accession and Version

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