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    Camk2g calcium/calmodulin-dependent protein kinase II gamma [ Rattus norvegicus (Norway rat) ]

    Gene ID: 171140, updated on 6-Jun-2024

    Summary

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    Symbol
    Camk2gprovided by RGD
    Full Name
    calcium/calmodulin-dependent protein kinase II gammaprovided by RGD
    Primary source
    RGD:621802
    See related
    Ensembl:ENSRNOG00000009783 AllianceGenome:RGD:621802
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables calmodulin-dependent protein kinase activity. Involved in several processes, including protein autophosphorylation; regulation of protein localization to plasma membrane; and response to hypoxia. Predicted to be located in postsynaptic density. Predicted to be part of calcium- and calmodulin-dependent protein kinase complex. Predicted to be active in cytoplasm and neuron projection. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability. Orthologous to human CAMK2G (calcium/calmodulin dependent protein kinase II gamma). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 299.9), Muscle (RPKM 278.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Camk2g in Genome Data Viewer
    Location:
    15p16
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (3553238..3612310)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (3504017..3563050)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (3936721..3995740)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120096900 Neighboring gene plasminogen activator, urokinase Neighboring gene uncharacterized LOC108352872 Neighboring gene N-deacetylase and N-sulfotransferase 2 Neighboring gene zinc finger, SWIM-type containing 8 Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. miR-219-5p targets CaMKIIγ to attenuate morphine tolerance in rats. Wang J, et al. Oncotarget, 2017 Apr 25. PMID 28423675, Free PMC Article
    2. One cell model establishment to inhibit CaMKII(γ) mRNA expression in the dorsal root ganglion neuron by RNA interfere. Wen X, et al. Artif Cells Nanomed Biotechnol, 2017 Sep. PMID 27685016
    3. γCaMKII shuttles Ca²⁺/CaM to the nucleus to trigger CREB phosphorylation and gene expression. Ma H, et al. Cell, 2014 Oct 9. PMID 25303525, Free PMC Article
    4. CaMKII protects MKP-1 from proteasome degradation in endothelial cells. Ciccarelli M, et al. Cell Signal, 2014 Oct. PMID 25007998
    5. DY-9760e inhibits endothelin-1-induced cardiomyocyte hypertrophy through inhibition of CaMKII and ERK activities. Lu YM, et al. Cardiovasc Ther, 2009 Spring. PMID 19207476

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Cx43 overexpression reduce the incidence of obstructive sleep apnea associated atrial fibrillation via the CaMKgamma/HIF-1 axis.
      Title: Cx43 overexpression reduce the incidence of obstructive sleep apnea associated atrial fibrillation via the CaMKⅡγ/HIF-1 axis.
    2. MicroRNA-219a-5p-mediated inhibition of CaMKIIgamma facilitates vestibular compensation in acute vertigo by promoting protein kinase C expression.
      Title: MicroRNA-219a-5p-mediated inhibition of CaMKIIγ facilitates vestibular compensation in acute vertigo by promoting protein kinase C expression.
    3. Inhibition of MicroRNA 219 Expression Protects Synaptic Plasticity via Activating NMDAR1, CaMKIIgamma, and p-CREB after Microwave Radiation.
      Title: Inhibition of MicroRNA 219 Expression Protects Synaptic Plasticity via Activating NMDAR1, CaMKIIγ, and p-CREB after Microwave Radiation.
    4. Thymine DNA glycosylase plays a key role in regulating CaMKIIgamma expression in vascular smooth muscle cells through promoter cytosine methylation/demethylation.
      Title: Thymine DNA glycosylase is a key regulator of CaMKIIγ expression and vascular smooth muscle phenotype.
    5. miR-219-5p plays a crucial role in alleviating morphine tolerance by inhibiting the CaMKII/NMDA receptor pathway. Overexpression of miR-219-5p may be a potential strategy to ameliorate morphine tolerance.
      Title: miR-219-5p targets CaMKIIγ to attenuate morphine tolerance in rats.
    6. Those results showed that we successfully constructed one adenovirus vector that can infect the dorsal root ganglion neuron to inhibit the CaMKIIgamma mRNA and protein expression. That will supply with one cell model for the CaMKIIgamma function study.
      Title: One cell model establishment to inhibit CaMKII(γ) mRNA expression in the dorsal root ganglion neuron by RNA interfere.
    7. CaMKII gamma, besides phosphorylation through the known ras-raf-mek pathway, can regulate also dephosphorylation of p44/p42 by modulation of MKP-1 level.
      Title: CaMKII protects MKP-1 from proteasome degradation in endothelial cells.
    8. Study reports a mechanism that mediates long-distance communication within cells: a shuttle that transports Ca(2+)/calmodulin from the surface membrane to the nucleus; the shuttle protein is gammaCaMKII, its phosphorylation at Thr287 by betaCaMKII protects the Ca(2+)/CaM signal, and CaN triggers its nuclear translocation.
      Title: γCaMKII shuttles Ca²⁺/CaM to the nucleus to trigger CREB phosphorylation and gene expression.
    9. CaMKIIgamma is required for the CaMKII-dependent regulation of ASK1, affecting the apoptosis of a biologically important cell type under spinal cord injury.
      Title: CaMKII activates ASK1 to induce apoptosis of spinal astrocytes under oxygen-glucose deprivation.
    10. translocation of CaM and CaMKII from the cytoplasm to the nucleus serves as messengers to transmit the pathogenic signal elicited in the surface membrane and in the RyR2 to the nuclear transcriptional sites to activate hypertrophy.
      Title: Intracellular translocation of calmodulin and Ca2+/calmodulin-dependent protein kinase II during the development of hypertrophy in neonatal cardiomyocytes.
    Submit: New GeneRIF Correction See all GeneRIFs (15)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calmodulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calmodulin-dependent protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calmodulin-dependent protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables calmodulin-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables calmodulin-dependent protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within G1/S transition of mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within calcium ion transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of long-term neuronal synaptic plasticity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of neuron projection development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of postsynaptic membrane neurotransmitter receptor levels IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of protein localization to plasma membrane IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of relaxation of cardiac muscle ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in response to hypoxia IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in response to oxidative stress IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of calcium- and calmodulin-dependent protein kinase complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    		  
    located_in organelle IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in postsynaptic cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in sarcoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    calcium/calmodulin-dependent protein kinase type II subunit gamma
    Names
    Ca+2/calmodulin-dependent protein kinase II gamma
    caM kinase II subunit gamma
    caM-kinase II gamma chain
    caMK-II subunit gamma
    calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma
    calcium/calmodulin-dependent protein kinase type II gamma chain
    calcium/calmodulin-dependent protein kinase type II subunit gamma-like
    NP_598289.1
    XP_008768708.1
    XP_008768709.1
    XP_008768710.1
    XP_008768711.1
    XP_008768712.1
    XP_008768713.1
    XP_008768714.1
    XP_008768715.1
    XP_008768716.1
    XP_008768717.1
    XP_008768718.1
    XP_008768719.1
    XP_008768720.1
    XP_008768721.1
    XP_017455064.1
    XP_017455065.1
    XP_017455066.1
    XP_038948899.1
    XP_038948900.1
    XP_063130002.1
    XP_063130003.1
    XP_063130004.1
    XP_063130005.1
    XP_063130006.1
    XP_063130007.1
    XP_063130008.1
    XP_063130009.1
    XP_063130010.1
    XP_063130011.1
    XP_063130012.1
    XP_063130013.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133605.1 → NP_598289.1  calcium/calmodulin-dependent protein kinase type II subunit gamma

      See identical proteins and their annotated locations for NP_598289.1

      Status: PROVISIONAL

      Source sequence(s)
      J04063
      UniProtKB/Swiss-Prot
      P11730, Q64003, Q64004
      UniProtKB/TrEMBL
      A0A8I5ZX06
      Related
      ENSRNOP00000062321.3, ENSRNOT00000066163.5
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:395 → 522
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      3553238..3612310
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017599577.3 → XP_017455066.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X17

      UniProtKB/TrEMBL
      A0A8I6AC70
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:374 → 501
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    2. XM_008770489.4 → XP_008768711.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X3

      See identical proteins and their annotated locations for XP_008768711.1

      UniProtKB/TrEMBL
      A0A8I6AC70
      Related
      ENSRNOP00000090296.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:435 → 562
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    3. XM_008770496.4 → XP_008768718.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X12

      See identical proteins and their annotated locations for XP_008768718.1

      UniProtKB/TrEMBL
      A0A8I5Y738, A0A8I6AC70
      Related
      ENSRNOP00000077055.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:397 → 524
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    4. XM_017599576.3 → XP_017455065.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X9

      UniProtKB/TrEMBL
      A0A8I6AC70
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:412 → 539
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    5. XM_063273932.1 → XP_063130002.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X5

      UniProtKB/TrEMBL
      A0A8I5ZV59, A0A8I6AC70

    6. XM_008770491.4 → XP_008768713.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X5

      See identical proteins and their annotated locations for XP_008768713.1

      UniProtKB/TrEMBL
      A0A8I5ZV59, A0A8I6AC70
      Related
      ENSRNOP00000083090.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:424 → 551
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    7. XM_063273936.1 → XP_063130006.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X14

      UniProtKB/TrEMBL
      A0A8I6AC70

    8. XM_008770497.4 → XP_008768719.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X14

      See identical proteins and their annotated locations for XP_008768719.1

      UniProtKB/TrEMBL
      A0A8I6AC70
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:386 → 513
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    9. XM_008770495.4 → XP_008768717.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X11

      See identical proteins and their annotated locations for XP_008768717.1

      UniProtKB/TrEMBL
      A0A8I6A5E2, A0A8I6AC70
      Related
      ENSRNOP00000088587.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:401 → 528
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    10. XM_063273938.1 → XP_063130008.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X18

      UniProtKB/TrEMBL
      A0A8I5ZX06

    11. XM_008770499.4 → XP_008768721.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X18

      See identical proteins and their annotated locations for XP_008768721.1

      UniProtKB/TrEMBL
      A0A8I5ZX06
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:363 → 490
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    12. XM_039092972.2 → XP_038948900.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X24

      Conserved Domains (1) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II

    13. XM_008770487.4 → XP_008768709.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1

      See identical proteins and their annotated locations for XP_008768709.1

      UniProtKB/TrEMBL
      A0A8I6AC70
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:456 → 583
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    14. XM_008770486.4 → XP_008768708.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1

      See identical proteins and their annotated locations for XP_008768708.1

      UniProtKB/TrEMBL
      A0A8I6AC70
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:456 → 583
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    15. XM_063273933.1 → XP_063130003.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X7

      UniProtKB/TrEMBL
      A0A8I6AC70

    16. XM_008770490.4 → XP_008768712.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X4

      See identical proteins and their annotated locations for XP_008768712.1

      UniProtKB/TrEMBL
      A0A8I6AC70
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:433 → 560
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    17. XM_008770488.4 → XP_008768710.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X2

      See identical proteins and their annotated locations for XP_008768710.1

      UniProtKB/TrEMBL
      A0A8I6AC70
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:445 → 572
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    18. XM_008770492.4 → XP_008768714.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X6

      See identical proteins and their annotated locations for XP_008768714.1

      UniProtKB/TrEMBL
      A0A8I6AC70
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:422 → 549
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    19. XM_008770493.4 → XP_008768715.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X7

      See identical proteins and their annotated locations for XP_008768715.1

      UniProtKB/TrEMBL
      A0A8I6AC70
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:418 → 545
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    20. XM_063273934.1 → XP_063130004.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X10

      UniProtKB/TrEMBL
      A0A8I6AC70

    21. XM_008770494.4 → XP_008768716.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X10

      See identical proteins and their annotated locations for XP_008768716.1

      UniProtKB/TrEMBL
      A0A8I6AC70
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:407 → 534
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    22. XM_008770498.4 → XP_008768720.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X15

      See identical proteins and their annotated locations for XP_008768720.1

      UniProtKB/TrEMBL
      A0A8I5ZX06, A0A8I6AD45
      Related
      ENSRNOP00000090198.1
      Conserved Domains (2) summary
      cd14086
      Location:12 → 303
      STKc_CaMKII; Catalytic domain of the Serine/Threonine kinase, Calcium/calmodulin-dependent protein kinase Type II
      pfam08332
      Location:384 → 511
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain

    23. XM_063273940.1 → XP_063130010.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X20

      UniProtKB/TrEMBL
      A0A8I6AC70

    24. XM_063273939.1 → XP_063130009.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X19

      UniProtKB/TrEMBL
      A0A8I6AC70

    25. XM_063273942.1 → XP_063130012.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X21

      UniProtKB/TrEMBL
      A0A8I5ZX06

    26. XM_063273935.1 → XP_063130005.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X13

      UniProtKB/TrEMBL
      A0A8I6AC70

    27. XM_063273937.1 → XP_063130007.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X16

      UniProtKB/TrEMBL
      A0A8I6AC70

    28. XM_063273941.1 → XP_063130011.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X20

      UniProtKB/TrEMBL
      A0A8I6AC70

    29. XM_017599575.3 → XP_017455064.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X8

      UniProtKB/TrEMBL
      A0A8I6AC70

    30. XM_039092971.1 → XP_038948899.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X22

      Conserved Domains (2) summary
      pfam08332
      Location:234 → 361
      CaMKII_AD; Calcium/calmodulin dependent protein kinase II association domain
      cl21453
      Location:11 → 81
      PKc_like; Protein Kinases, catalytic domain

    31. XM_063273943.1 → XP_063130013.1  calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X23

    RNA

    1. XR_010057798.1 RNA Sequence

    2. XR_010057800.1 RNA Sequence

    3. XR_010057797.1 RNA Sequence

    4. XR_001841253.3 RNA Sequence

    5. XR_010057799.1 RNA Sequence

    6. XR_010057801.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P11730.1 GenPept UniProtKB/Swiss-Prot:P11730

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