Enoph1 enolase-phosphatase 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Enoph1provided by RGD
Official Full Name: enolase-phosphatase 1provided by RGD
Primary source: RGD:1309016
See related: Ensembl:ENSRNOG00000002262 AllianceGenome:RGD:1309016
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1309016
Summary: Predicted to enable acireductone synthase activity. Predicted to be involved in L-methionine salvage from methylthioadenosine. Predicted to be located in cytoplasm and nucleus. Orthologous to human ENOPH1 (enolase-phosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Adrenal (RPKM 179.0), Brain (RPKM 157.3) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 14p22

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	14	NC_086032.1 (9835626..9862051, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	14	NC_051349.1 (9531336..9557797, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	14	NC_005113.4 (11172359..11198799, complement)

Chromosome 14 - NC_086032.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables 2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity	IEA Inferred from Electronic Annotation more info
enables 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity	IEA Inferred from Electronic Annotation more info
enables acireductone synthase activity	IBA Inferred from Biological aspect of Ancestor more info
enables acireductone synthase activity	IEA Inferred from Electronic Annotation more info
enables acireductone synthase activity	ISO Inferred from Sequence Orthology more info
enables acireductone synthase activity	ISS Inferred from Sequence or Structural Similarity more info
enables magnesium ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in L-methionine salvage from S-adenosylmethionine	IEA Inferred from Electronic Annotation more info
involved_in L-methionine salvage from methylthioadenosine	IBA Inferred from Biological aspect of Ancestor more info
involved_in L-methionine salvage from methylthioadenosine	IEA Inferred from Electronic Annotation more info
involved_in L-methionine salvage from methylthioadenosine	ISO Inferred from Sequence Orthology more info
involved_in L-methionine salvage from methylthioadenosine	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: enolase-phosphatase E1

Names: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; E-1 enzyme; MASA homolog

NP_001009391.1

EC 3.1.3.77

XP_017454658.1

EC 3.1.3.77

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001009391.1 → NP_001009391.1 enolase-phosphatase E1

See identical proteins and their annotated locations for NP_001009391.1

Status: PROVISIONAL

Source sequence(s)

BC087697

UniProtKB/Swiss-Prot

Q5PPH0

UniProtKB/TrEMBL

A0A8I6ADH3, A6K613

Related

ENSRNOP00000003083.3, ENSRNOT00000003083.4

Conserved Domains (1) summary

cd01629
Location:12 → 231

HAD_EP; Enolase-phosphatase similar to human enolase-phosphatase E1 and and Xanthomonas oryzae pv. Oryzae enolase-phosphatase Xep