U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Raver2 ribonucleoprotein, PTB-binding 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362551, updated on 2-Apr-2024

    Summary

    Go to the top of the page Help
    Symbol
    Raver2provided by RGD
    Full Name
    ribonucleoprotein, PTB-binding 2provided by RGD
    Primary source
    RGD:1307610
    See related
    Ensembl:ENSRNOG00000023812 AllianceGenome:RGD:1307610
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307610
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be active in nucleus. Orthologous to human RAVER2 (ribonucleoprotein, PTB binding 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Lung (RPKM 185.3), Adrenal (RPKM 138.6) and 9 other tissues See more
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Raver2 in Genome Data Viewer
    Location:
    5q33
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (120796807..120898281)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (115700985..115780465)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (119903449..119982723)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene cache domain containing 1 Neighboring gene uncharacterized LOC134479016 Neighboring gene U6 spliceosomal RNA Neighboring gene Janus kinase 1 Neighboring gene small nucleolar RNA SNORA70

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Raver2, a new member of the hnRNP family. Kleinhenz B, et al. FEBS Lett, 2005 Aug 15. PMID 16051233
    2. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    ribonucleoprotein PTB-binding 2
    Names
    ribonucleoprotein PTB-binding 2-like

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191867.2 → NP_001178796.1  ribonucleoprotein PTB-binding 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A6JRN1
      Conserved Domains (2) summary
      cd12666
      Location:132 → 208
      RRM2_RAVER2; RNA recognition motif 2 in vertebrate ribonucleoprotein PTB-binding 2 (raver-2)
      cl17169
      Location:218 → 314
      RRM_SF; RNA recognition motif (RRM) superfamily

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      120796807..120898281
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063287969.1 → XP_063144039.1  ribonucleoprotein PTB-binding 2 isoform X3

    2. XM_063287970.1 → XP_063144040.1  ribonucleoprotein PTB-binding 2 isoform X3

    3. XM_039110292.2 → XP_038966220.1  ribonucleoprotein PTB-binding 2 isoform X1

      Conserved Domains (3) summary
      cd12666
      Location:244 → 320
      RRM2_RAVER2; RNA recognition motif 2 (RRM2) found in vertebrate ribonucleoprotein PTB-binding 2 (raver-2)
      cd12668
      Location:330 → 426
      RRM3_RAVER2; RNA recognition motif 3 (RRM3) found found in vertebrate ribonucleoprotein PTB-binding 2 (raver-2)
      cl17169
      Location:207 → 240
      RRM_SF; RNA recognition motif (RRM) superfamily

    4. XM_006238451.5 → XP_006238513.1  ribonucleoprotein PTB-binding 2 isoform X2

      UniProtKB/TrEMBL
      A6JRN1, D3ZD78
      Related
      ENSRNOP00000031675.5
      Conserved Domains (2) summary
      cd12666
      Location:132 → 208
      RRM2_RAVER2; RNA recognition motif 2 in vertebrate ribonucleoprotein PTB-binding 2 (raver-2)
      cl17169
      Location:218 → 314
      RRM_SF; RNA recognition motif (RRM) superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools