U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PAK1 p21 (RAC1) activated kinase 1 [ Gallus gallus (chicken) ]

    Gene ID: 419083, updated on 5-Mar-2024

    Summary

    Go to the top of the page Help
    Symbol
    PAK1provided by CGNC
    Full Name
    p21 (RAC1) activated kinase 1provided by CGNC
    Primary source
    CGNC:432
    See related
    Ensembl:ENSGALG00010002102
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PAK1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (192921986..192989287)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (192991543..193058789)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene microRNA mir-12215 Neighboring gene chloride nucleotide-sensitive channel 1A Neighboring gene uncharacterized LOC107055756 Neighboring gene aquaporin 11 Neighboring gene glycerophosphodiester phosphodiesterase domain containing 2 Neighboring gene myosin VIIA

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of axonogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    serine/threonine-protein kinase PAK 1
    Names
    p21 protein (Cdc42/Rac)-activated kinase 1
    p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
    NP_001155844.1
    XP_015136339.1
    XP_015136341.1
    XP_040556531.1
    XP_040556538.1
    XP_040556552.1
    XP_040556563.1
    XP_040556573.1
    XP_040556578.1
    XP_040556582.1
    XP_040556587.1
    XP_040556594.1
    XP_040556635.1
    XP_040556642.1
    XP_046764362.1
    XP_046764363.1
    XP_046764364.1
    XP_046764365.1
    XP_046764366.1
    XP_046764367.1
    XP_046764368.1
    XP_046764369.1
    XP_046764370.1
    XP_046764371.1
    XP_046764372.1
    XP_046764373.1
    XP_046764374.1
    XP_046764375.1
    XP_046764376.1
    XP_046764377.1
    XP_046764378.1
    XP_046764379.1
    XP_046764380.1
    XP_046764381.1
    XP_046764382.1
    XP_046764383.1
    XP_046798313.1
    XP_046798329.1
    XP_046798332.1
    XP_046798334.1
    XP_046798337.1
    XP_046798339.1
    XP_046798341.1
    XP_046798343.1
    XP_046798344.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001162372.5 → NP_001155844.1  serine/threonine-protein kinase PAK 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000028
      UniProtKB/TrEMBL
      E1C3P6
      Conserved Domains (2) summary
      cd06654
      Location:248 → 543
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      192921986..192989287
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040700653.2 → XP_040556587.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6
      Conserved Domains (2) summary
      cd06654
      Location:248 → 543
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    2. XM_040700701.2 → XP_040556635.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6
      Conserved Domains (2) summary
      cd06654
      Location:248 → 543
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    3. XM_046942373.1 → XP_046798329.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    4. XM_046942383.1 → XP_046798339.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    5. XM_046942385.1 → XP_046798341.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    6. XM_046942378.1 → XP_046798334.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    7. XM_046942357.1 → XP_046798313.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    8. XM_046942381.1 → XP_046798337.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    9. XM_040700708.2 → XP_040556642.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6
      Conserved Domains (2) summary
      cd06654
      Location:248 → 543
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    10. XM_046942376.1 → XP_046798332.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    11. XM_040700648.2 → XP_040556582.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6
      Conserved Domains (2) summary
      cd06654
      Location:248 → 543
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    12. XM_040700618.2 → XP_040556552.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6
      Conserved Domains (2) summary
      cd06654
      Location:248 → 543
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    13. XM_040700629.2 → XP_040556563.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6
      Conserved Domains (2) summary
      cd06654
      Location:248 → 543
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    14. XM_040700604.2 → XP_040556538.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6
      Conserved Domains (2) summary
      cd06654
      Location:248 → 543
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    15. XM_040700644.2 → XP_040556578.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6
      Conserved Domains (2) summary
      cd06654
      Location:248 → 543
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    16. XM_040700597.2 → XP_040556531.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6
      Related
      ENSGALP00010002842.1, ENSGALT00010004716.1
      Conserved Domains (2) summary
      cd06654
      Location:248 → 543
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    17. XM_040700639.2 → XP_040556573.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6
      Conserved Domains (2) summary
      cd06654
      Location:248 → 543
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    18. XM_046942387.1 → XP_046798343.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    19. XM_015280853.4 → XP_015136339.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6
      Conserved Domains (2) summary
      cd06654
      Location:248 → 543
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    20. XM_015280855.4 → XP_015136341.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6
      Conserved Domains (2) summary
      cd06654
      Location:248 → 543
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    21. XM_046942388.1 → XP_046798344.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    22. XM_040700660.2 → XP_040556594.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6
      Conserved Domains (2) summary
      cd06654
      Location:248 → 543
      STKc_PAK1; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 1
      pfam00786
      Location:74 → 132
      PBD; P21-Rho-binding domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      192991543..193058789
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046908424.1 → XP_046764380.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    2. XM_046908427.1 → XP_046764383.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    3. XM_046908417.1 → XP_046764373.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    4. XM_046908422.1 → XP_046764378.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    5. XM_046908423.1 → XP_046764379.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    6. XM_046908419.1 → XP_046764375.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    7. XM_046908413.1 → XP_046764369.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    8. XM_046908420.1 → XP_046764376.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    9. XM_046908416.1 → XP_046764372.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    10. XM_046908418.1 → XP_046764374.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    11. XM_046908415.1 → XP_046764371.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    12. XM_046908410.1 → XP_046764366.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    13. XM_046908411.1 → XP_046764367.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    14. XM_046908408.1 → XP_046764364.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    15. XM_046908414.1 → XP_046764370.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    16. XM_046908409.1 → XP_046764365.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    17. XM_046908412.1 → XP_046764368.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    18. XM_046908425.1 → XP_046764381.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    19. XM_046908406.1 → XP_046764362.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    20. XM_046908407.1 → XP_046764363.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    21. XM_046908426.1 → XP_046764382.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6

    22. XM_046908421.1 → XP_046764377.1  serine/threonine-protein kinase PAK 1 isoform X1

      UniProtKB/TrEMBL
      E1C3P6
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.