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    DAPK1 death associated protein kinase 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 484142, updated on 8-Mar-2024

    Summary

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    Official Symbol
    DAPK1provided by VGNC
    Official Full Name
    death associated protein kinase 1provided by VGNC
    Primary source
    VGNC:VGNC:39770
    See related
    Ensembl:ENSCAFG00845005073
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 1 NC_051805.1 (72583435..72753483, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 1 NC_006583.4 (73041924..73209647, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 1 NC_049222.1 (72866793..73034612, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 1 NC_049261.1 (72395534..72563288, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 1 NC_049742.1 (72161011..72329008, complement)

    Chromosome 1 - NC_051805.1Genomic Context describing neighboring genes Neighboring gene methylsterol monooxygenase 1-like Neighboring gene procathepsin L Neighboring gene uncharacterized LOC119870814 Neighboring gene uncharacterized LOC111096369 Neighboring gene uncharacterized LOC106559361

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    death-associated protein kinase 1
    NP_001184086.1
    XP_038509443.1
    XP_038509444.1
    XP_038509445.1
    XP_038509446.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001197157.1 → NP_001184086.1  death-associated protein kinase 1

      See identical proteins and their annotated locations for NP_001184086.1

      Status: VALIDATED

      Source sequence(s)
      HQ189123
      UniProtKB/TrEMBL
      A0A8C0LDP8, A0A8C0PLR5, A0A8C0RUI2, A0A8I3NAR0, E2JE41, F1PML8
      Related
      ENSCAFP00845007168.1, ENSCAFT00845009093.1
      Conserved Domains (6) summary
      PLN03192
      Location:560 → 768
      PLN03192; Voltage-dependent potassium channel; Provisional
      COG0666
      Location:371 → 470
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd08782
      Location:1308 → 1393
      Death_DAPK1; Death domain found in death-associated protein kinase 1
      cd14194
      Location:7 → 275
      STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1
      sd00045
      Location:412 → 442
      ANK; ANK repeat [structural motif]
      cl39094
      Location:428 → 639
      Ank_2; Ankyrin repeats (3 copies)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051805.1 Reference ROS_Cfam_1.0

      Range
      72583435..72753483 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038653517.1 → XP_038509445.1  death-associated protein kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LDP8, A0A8C0PLR5, A0A8C0RUI2, A0A8I3NAR0, E2JE41, F1PML8
      Conserved Domains (6) summary
      PLN03192
      Location:560 → 768
      PLN03192; Voltage-dependent potassium channel; Provisional
      COG0666
      Location:371 → 470
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd08782
      Location:1308 → 1393
      Death_DAPK1; Death domain found in death-associated protein kinase 1
      cd14194
      Location:7 → 275
      STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1
      sd00045
      Location:412 → 442
      ANK; ANK repeat [structural motif]
      cl39094
      Location:428 → 639
      Ank_2; Ankyrin repeats (3 copies)

    2. XM_038653516.1 → XP_038509444.1  death-associated protein kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LDP8, A0A8C0PLR5, A0A8C0RUI2, A0A8I3NAR0, E2JE41, F1PML8
      Conserved Domains (6) summary
      PLN03192
      Location:560 → 768
      PLN03192; Voltage-dependent potassium channel; Provisional
      COG0666
      Location:371 → 470
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd08782
      Location:1308 → 1393
      Death_DAPK1; Death domain found in death-associated protein kinase 1
      cd14194
      Location:7 → 275
      STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1
      sd00045
      Location:412 → 442
      ANK; ANK repeat [structural motif]
      cl39094
      Location:428 → 639
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_038653518.1 → XP_038509446.1  death-associated protein kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LDP8, A0A8C0PLR5, A0A8C0RUI2, A0A8I3NAR0, E2JE41, F1PML8
      Conserved Domains (6) summary
      PLN03192
      Location:560 → 768
      PLN03192; Voltage-dependent potassium channel; Provisional
      COG0666
      Location:371 → 470
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd08782
      Location:1308 → 1393
      Death_DAPK1; Death domain found in death-associated protein kinase 1
      cd14194
      Location:7 → 275
      STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1
      sd00045
      Location:412 → 442
      ANK; ANK repeat [structural motif]
      cl39094
      Location:428 → 639
      Ank_2; Ankyrin repeats (3 copies)

    4. XM_038653515.1 → XP_038509443.1  death-associated protein kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8C0LDP8, A0A8C0PLR5, A0A8C0RUI2, A0A8I3NAR0, E2JE41, F1PML8
      Conserved Domains (6) summary
      PLN03192
      Location:560 → 768
      PLN03192; Voltage-dependent potassium channel; Provisional
      COG0666
      Location:371 → 470
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd08782
      Location:1308 → 1393
      Death_DAPK1; Death domain found in death-associated protein kinase 1
      cd14194
      Location:7 → 275
      STKc_DAPK1; Catalytic domain of the Serine/Threonine Kinase, Death-Associated Protein Kinase 1
      sd00045
      Location:412 → 442
      ANK; ANK repeat [structural motif]
      cl39094
      Location:428 → 639
      Ank_2; Ankyrin repeats (3 copies)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049261.1 Alternate UMICH_Zoey_3.1

      Range
      72395534..72563288 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049742.1 Alternate UNSW_CanFamBas_1.0

      Range
      72161011..72329008 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049222.1 Alternate UU_Cfam_GSD_1.0

      Range
      72866793..73034612 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      73041924..73209647 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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