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    Dipk2a divergent protein kinase domain 2A [ Mus musculus (house mouse) ]

    Gene ID: 68861, updated on 12-May-2024

    Summary

    Official Symbol
    Dipk2aprovided by MGI
    Official Full Name
    divergent protein kinase domain 2Aprovided by MGI
    Primary source
    MGI:MGI:1916111
    See related
    Ensembl:ENSMUSG00000045414 AllianceGenome:MGI:1916111
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    HASF; GoPro49; 1190002N15Rik
    Summary
    Acts upstream of or within negative regulation of smooth muscle cell apoptotic process. Located in COPI-coated vesicle and extracellular region. Is expressed in several structures, including embryo mesenchyme; hair follicle; jaw; musculoskeletal system; and nervous system. Orthologous to human DIPK2A (divergent protein kinase domain 2A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in lung adult (RPKM 26.4), ovary adult (RPKM 25.0) and 27 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    Location:
    9 E3.3; 9 49.03 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (94399917..94420134, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (94517864..94538081, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46148 Neighboring gene predicted gene, 31957 Neighboring gene predicted gene, 39404 Neighboring gene STARR-seq mESC enhancer starr_24923 Neighboring gene predicted gene, 24178

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    part_of COPI vesicle coat IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of COPI vesicle coat ISO
    Inferred from Sequence Orthology
    more info
     
    located_in COPI-coated vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    divergent protein kinase domain 2A
    Names
    Golgi Protein of 49 kDa
    Golgi protein GoPro49
    UPF0672 protein C3orf58 homolog
    deleted in autism protein 1 homolog
    hypoxia and AKT-induced stem cell factor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033145.2NP_001028317.2  divergent protein kinase domain 2A precursor

      See identical proteins and their annotated locations for NP_001028317.2

      Status: VALIDATED

      Source sequence(s)
      AC160129
      Consensus CDS
      CCDS40725.1
      UniProtKB/Swiss-Prot
      E9Q9E9, Q3USZ8
      Related
      ENSMUSP00000108651.2, ENSMUST00000113028.2
      Conserved Domains (1) summary
      pfam12260
      Location:206405
      PIP49_C; Protein-kinase domain of FAM69

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      94399917..94420134 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)