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    PF3D7_1468700 eukaryotic initiation factor 4A [ Plasmodium falciparum 3D7 ]

    Gene ID: 812237, updated on 17-May-2024

    Summary

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    Gene symbol
    PF3D7_1468700
    Gene description
    eukaryotic initiation factor 4A
    Primary source
    PlasmoDB:PF3D7_1468700
    Locus tag
    PF3D7_1468700
    Gene type
    protein coding
    RNA name
    eukaryotic initiation factor 4A
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
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    Genomic context

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    See PF3D7_1468700 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    4
    Sequence:
    Chromosome: 14; NC_037283.1 (2825370..2826918)

    Chromosome 14 - NC_037283.1Genomic Context describing neighboring genes Neighboring gene derlin-1 Neighboring gene aminophospholipid transporter, putative Neighboring gene splicing factor U2AF large subunit, putative Neighboring gene zinc finger protein, putative

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037283.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Enhanced purification and characterization of the PfeIF4A (PfH45) helicase from Plasmodium falciparum using a codon-optimised clone. Evans L, et al. Protein Expr Purif, 2012 Sep. PMID 22750398
    2. Isolation and functional characterization of eIF4F components and poly(A)-binding protein from Plasmodium falciparum. Tuteja R, et al. Parasitol Int, 2009 Dec. PMID 19751846
    3. Food vacuole proteome of the malarial parasite Plasmodium falciparum. Lamarque M, et al. Proteomics Clin Appl, 2008 Sep. PMID 21136929
    4. Proteomic analysis of extracellular vesicles from a Plasmodium falciparum Kenyan clinical isolate defines a core parasite secretome. Abdi A, et al. Wellcome Open Res, 2017. PMID 28944300, Free PMC Article
    5. Functional Characterization of the m(6)A-Dependent Translational Modulator PfYTH.2 in the Human Malaria Parasite. Sinha A, et al. mBio, 2021 Apr 27. PMID 33906926, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables 3'-5' DNA/RNA helicase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ATP hydrolysis activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA binding HDA PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular vesicle HDA PubMed 
    located_in food vacuole HDA PubMed 
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    eukaryotic initiation factor 4A
    XP_001348829.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037283.1 Reference assembly

      Range
      2825370..2826918
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001348793.1 → XP_001348829.1  eukaryotic initiation factor 4A [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001348829.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024UY98, A0A024WIB5, A0A024X0H4, A0A0L0CYX2, A0A0L1IE72, A0A0L7K5Y6, A0A0L7M3H6, A0A2I0C1J7, Q2PZH3, Q8IKF0, W7FD46, W7FQU2, W7JPL6
      Conserved Domains (1) summary
      PTZ00424
      Location:1 → 398
      PTZ00424; helicase 45; Provisional
    Nucleotide Protein
    Heading Accession and Version

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