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    Slc34a1 solute carrier family 34 member 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25548, updated on 6-May-2021

    Summary

    Official Symbol
    Slc34a1provided by RGD
    Official Full Name
    solute carrier family 34 member 1provided by RGD
    Primary source
    RGD:3708
    See related
    Ensembl:ENSRNOG00000015262
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Npt2; NaPi-2; NaPi2A; Slc17a2
    Summary
    membrane carrier protein that may be involved with active transport of phosphate into cells via sodium cotransport [RGD, Feb 2006]
    Expression
    Restricted expression toward (RPKM 4338.1) See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Slc34a1 in Genome Data Viewer
    Location:
    17p14
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    108 current mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (9218876..9233852, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (9747766..9762739, complement)

    Chromosome 17 - NC_051352.1Genomic Context describing neighboring genes Neighboring gene coagulation factor XII Neighboring gene profilin 3 Neighboring gene U6 spliceosomal RNA Neighboring gene regulator of G-protein signaling 14

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables PDZ domain binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein-containing complex binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables sodium:phosphate symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables sodium:phosphate symporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables sodium:phosphate symporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in arsenate ion transmembrane transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within bone remodeling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular phosphate ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in cellular response to metal ion IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in cellular response to parathyroid hormone stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in cellular response to staurosporine IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in dentinogenesis IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in gentamycin metabolic process IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in glycoprotein metabolic process IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in indole metabolic process IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in kidney development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in ossification IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in phosphate ion homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in phosphate ion transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in phosphate ion transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of membrane potential IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of membrane potential IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of phosphate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of sodium-dependent phosphate transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of sodium-dependent phosphate transport IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in positive regulation of sodium-dependent phosphate transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in response to cadmium ion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to drug IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to estradiol IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to growth hormone IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to lead ion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to magnesium ion IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to mercury ion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to nutrient IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to parathyroid hormone IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to peptide IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to peptide hormone IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to potassium ion IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to thyroid hormone IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to vitamin A IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in sodium ion import across plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in sodium-dependent phosphate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in sodium-dependent phosphate transport IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in tricarboxylic acid metabolic process IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in apical plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in brush border IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in brush border membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intrinsic component of plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane raft IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitotic spindle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitotic spindle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    sodium-dependent phosphate transport protein 2A
    Names
    Na(+)-dependent phosphate cotransporter 2A
    Na(+)/Pi cotransporter 2A
    naPi-2a
    sodium-phosphate co-transporter type II
    sodium-phosphate transport protein 2A
    sodium/phosphate cotransporter 2A
    solute carrier family 17 (sodium/hydrogen exchanger) member 2
    solute carrier family 34 (sodium phosphate), member 1
    solute carrier family 34 (type II sodium/phosphate cotransporter), member 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013030.2NP_037162.1  sodium-dependent phosphate transport protein 2A

      See identical proteins and their annotated locations for NP_037162.1

      Status: PROVISIONAL

      Source sequence(s)
      JACYVU010000284
      UniProtKB/Swiss-Prot
      Q06496
      Related
      ENSRNOP00000031764.4, ENSRNOT00000033749.5
      Conserved Domains (2) summary
      TIGR01013
      Location:108588
      2a58; Phosphate:Na+ Symporter (PNaS) Family
      pfam02690
      Location:113204
      Na_Pi_cotrans; Na+/Pi-cotransporter

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mRatBN7.2 Primary Assembly

    Genomic

    1. NC_051352.1 Reference mRatBN7.2 Primary Assembly

      Range
      9218876..9233852 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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