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    DOCK10 dedicator of cytokinesis 10 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 707649, updated on 5-Mar-2024

    Summary

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    Official Symbol
    DOCK10provided by VGNC
    Official Full Name
    dedicator of cytokinesis 10provided by VGNC
    Primary source
    VGNC:VGNC:71888
    See related
    Ensembl:ENSMMUG00000018139
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See DOCK10 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    60
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (112202150..112485413, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (107023690..107303929, complement)

    Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106992745 Neighboring gene cullin 3 Neighboring gene uncharacterized LOC114671433 Neighboring gene neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in dendritic spine morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dedicator of cytokinesis protein 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041765.1 Reference Mmul_10 Primary Assembly

      Range
      112202150..112485413 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015111179.2 → XP_014966665.1  dedicator of cytokinesis protein 10 isoform X6

      UniProtKB/TrEMBL
      H9FWW3
      Related
      ENSMMUP00000065549.1, ENSMMUT00000093622.1
      Conserved Domains (4) summary
      cd08697
      Location:671 → 860
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11699
      Location:1696 → 2143
      DHR2_DOCK10; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 10
      cd13267
      Location:182 → 302
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:45 → 155
      DUF3398; Domain of unknown function (DUF3398)

    2. XM_015111181.2 → XP_014966667.1  dedicator of cytokinesis protein 10 isoform X8

      UniProtKB/TrEMBL
      H9FWW2
      Related
      ENSMMUP00000067820.1, ENSMMUT00000107392.1
      Conserved Domains (5) summary
      cd08697
      Location:671 → 860
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11699
      Location:1696 → 2141
      DHR2_DOCK10; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 10
      cd13267
      Location:182 → 302
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam00169
      Location:182 → 289
      PH; PH domain
      pfam11878
      Location:66 → 153
      DUF3398; Domain of unknown function (DUF3398)

    3. XM_015111183.2 → XP_014966669.1  dedicator of cytokinesis protein 10 isoform X10

      UniProtKB/TrEMBL
      A0A1D5R9Z9
      Conserved Domains (5) summary
      cd08697
      Location:684 → 873
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd13267
      Location:195 → 315
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam00169
      Location:195 → 302
      PH; PH domain
      pfam11878
      Location:79 → 166
      DUF3398; Domain of unknown function (DUF3398)
      cl06123
      Location:1709 → 2123
      DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

    4. XM_015111178.2 → XP_014966664.1  dedicator of cytokinesis protein 10 isoform X5

      UniProtKB/TrEMBL
      A0A1D5R9Z9
      Conserved Domains (5) summary
      cd08697
      Location:684 → 873
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11699
      Location:1700 → 2147
      DHR2_DOCK10; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 10
      cd13267
      Location:195 → 315
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam00169
      Location:195 → 302
      PH; PH domain
      pfam11878
      Location:79 → 166
      DUF3398; Domain of unknown function (DUF3398)

    5. XM_015111184.2 → XP_014966670.1  dedicator of cytokinesis protein 10 isoform X11

      UniProtKB/TrEMBL
      A0A1D5R9Z9
      Conserved Domains (5) summary
      cd08697
      Location:684 → 873
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd13267
      Location:195 → 315
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam00169
      Location:195 → 302
      PH; PH domain
      pfam11878
      Location:79 → 166
      DUF3398; Domain of unknown function (DUF3398)
      cl06123
      Location:1709 → 2121
      DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins

    6. XM_015111174.2 → XP_014966660.1  dedicator of cytokinesis protein 10 isoform X1

      UniProtKB/TrEMBL
      A0A1D5R9Z9
      Conserved Domains (4) summary
      cd08697
      Location:684 → 873
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11699
      Location:1709 → 2156
      DHR2_DOCK10; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 10
      cd13267
      Location:195 → 315
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:58 → 168
      DUF3398; Domain of unknown function (DUF3398)

    7. XM_015111175.2 → XP_014966661.1  dedicator of cytokinesis protein 10 isoform X2

      UniProtKB/TrEMBL
      A0A1D5Q6G4, A0A1D5R9Z9
      Related
      ENSMMUP00000043630.2, ENSMMUT00000074287.2
      Conserved Domains (5) summary
      cd08697
      Location:684 → 873
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11699
      Location:1709 → 2154
      DHR2_DOCK10; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 10
      cd13267
      Location:195 → 315
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam00169
      Location:195 → 302
      PH; PH domain
      pfam11878
      Location:79 → 166
      DUF3398; Domain of unknown function (DUF3398)

    8. XM_015111176.2 → XP_014966662.1  dedicator of cytokinesis protein 10 isoform X3

      UniProtKB/TrEMBL
      H9FWW3
      Conserved Domains (5) summary
      cd08697
      Location:684 → 873
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11699
      Location:1709 → 2156
      DHR2_DOCK10; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 10
      cd13267
      Location:195 → 315
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam00169
      Location:195 → 302
      PH; PH domain
      pfam11878
      Location:79 → 166
      DUF3398; Domain of unknown function (DUF3398)

    9. XM_015111177.2 → XP_014966663.1  dedicator of cytokinesis protein 10 isoform X4

      UniProtKB/TrEMBL
      H9FWW2
      Conserved Domains (5) summary
      cd08697
      Location:684 → 873
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11699
      Location:1709 → 2154
      DHR2_DOCK10; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 10
      cd13267
      Location:195 → 315
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam00169
      Location:195 → 302
      PH; PH domain
      pfam11878
      Location:79 → 166
      DUF3398; Domain of unknown function (DUF3398)

    10. XM_028831155.1 → XP_028686988.1  dedicator of cytokinesis protein 10 isoform X7

      UniProtKB/TrEMBL
      F7F7Q3
      Conserved Domains (4) summary
      cd08697
      Location:665 → 854
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11699
      Location:1690 → 2137
      DHR2_DOCK10; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 10
      cd13267
      Location:176 → 296
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:39 → 149
      DUF3398; Domain of unknown function (DUF3398)

    11. XM_015111180.2 → XP_014966666.1  dedicator of cytokinesis protein 10 isoform X7

      UniProtKB/TrEMBL
      F7F7Q3
      Related
      ENSMMUP00000057140.2, ENSMMUT00000059970.2
      Conserved Domains (4) summary
      cd08697
      Location:665 → 854
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11699
      Location:1690 → 2137
      DHR2_DOCK10; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 10
      cd13267
      Location:176 → 296
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam11878
      Location:39 → 149
      DUF3398; Domain of unknown function (DUF3398)

    12. XM_015111182.2 → XP_014966668.1  dedicator of cytokinesis protein 10 isoform X9

      UniProtKB/TrEMBL
      F7F7Q3
      Related
      ENSMMUP00000023846.4, ENSMMUT00000025488.4
      Conserved Domains (5) summary
      cd08697
      Location:665 → 854
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd11699
      Location:1690 → 2135
      DHR2_DOCK10; Dock Homology Region 2, a GEF domain, of Class D Dedicator of Cytokinesis 10
      cd13267
      Location:176 → 296
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam00169
      Location:176 → 283
      PH; PH domain
      pfam11878
      Location:60 → 147
      DUF3398; Domain of unknown function (DUF3398)

    13. XM_015111185.2 → XP_014966671.1  dedicator of cytokinesis protein 10 isoform X12

      UniProtKB/TrEMBL
      A0A1D5R9Z9
      Conserved Domains (5) summary
      cd08697
      Location:684 → 873
      C2_Dock-D; C2 domains found in Dedicator Of CytoKinesis (Dock) class C proteins
      cd13267
      Location:195 → 315
      PH_DOCK-D; Dedicator of cytokinesis-D subfamily Pleckstrin homology (PH) domain
      pfam00169
      Location:195 → 302
      PH; PH domain
      pfam11878
      Location:79 → 166
      DUF3398; Domain of unknown function (DUF3398)
      cl06123
      Location:1700 → 2114
      DHR2_DOCK; Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins
    Nucleotide Protein
    Heading Accession and Version

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