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    MARK1 microtubule affinity regulating kinase 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 710695, updated on 5-Mar-2024

    Summary

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    Official Symbol
    MARK1provided by VGNC
    Official Full Name
    microtubule affinity regulating kinase 1provided by VGNC
    Primary source
    VGNC:VGNC:74658
    See related
    Ensembl:ENSMMUG00000022288
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See MARK1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (78121368..78264953)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (145665558..145809004, complement)

    Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene 60S acidic ribosomal protein P0 pseudogene Neighboring gene PRELI domain containing protein 3B-like Neighboring gene histone deacetylase 1-like Neighboring gene chromosome 1 C1orf115 homolog Neighboring gene uncharacterized LOC114680575

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables tau-protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in microtubule cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein kinase MARK1
    Names
    serine/threonine-protein kinase MARK1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041754.1 Reference Mmul_10 Primary Assembly

      Range
      78121368..78264953
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015115877.2 → XP_014971363.1  serine/threonine-protein kinase MARK1 isoform X1

      UniProtKB/TrEMBL
      F6X739, F6X788
      Related
      ENSMMUP00000029340.4, ENSMMUT00000031356.4
      Conserved Domains (4) summary
      cd12196
      Location:696 → 793
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:60 → 311
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14405
      Location:331 → 371
      UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
      cd14072
      Location:59 → 311
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    2. XM_015115881.2 → XP_014971367.1  serine/threonine-protein kinase MARK1 isoform X2

      UniProtKB/TrEMBL
      F6X739
      Conserved Domains (4) summary
      cd12196
      Location:695 → 792
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:60 → 311
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14405
      Location:331 → 371
      UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
      cd14072
      Location:59 → 311
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    3. XM_015115890.2 → XP_014971376.1  serine/threonine-protein kinase MARK1 isoform X4

      UniProtKB/TrEMBL
      F6X739
      Related
      ENSMMUP00000029342.4, ENSMMUT00000031359.4
      Conserved Domains (4) summary
      cd12196
      Location:680 → 777
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:60 → 311
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14405
      Location:331 → 371
      UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
      cd14072
      Location:59 → 311
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    4. XM_015115885.2 → XP_014971371.1  serine/threonine-protein kinase MARK1 isoform X3

      UniProtKB/TrEMBL
      F6X739
      Conserved Domains (4) summary
      cd12196
      Location:681 → 778
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:60 → 311
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14405
      Location:331 → 371
      UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
      cd14072
      Location:59 → 311
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    5. XM_015115902.2 → XP_014971388.1  serine/threonine-protein kinase MARK1 isoform X6

      UniProtKB/TrEMBL
      F6X739
      Conserved Domains (4) summary
      cd12196
      Location:586 → 683
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:1 → 201
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14405
      Location:221 → 261
      UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
      cl21453
      Location:1 → 201
      PKc_like; Protein Kinases, catalytic domain

    6. XM_015115895.2 → XP_014971381.1  serine/threonine-protein kinase MARK1 isoform X5

      UniProtKB/TrEMBL
      F6X739
      Conserved Domains (4) summary
      cd12196
      Location:608 → 705
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:15 → 223
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14405
      Location:243 → 283
      UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
      cl21453
      Location:10 → 223
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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