SIAH2 siah E3 ubiquitin protein ligase 2 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: SIAH2provided by VGNC
Official Full Name: siah E3 ubiquitin protein ligase 2provided by VGNC
Primary source: VGNC:VGNC:77215
See related: Ensembl:ENSMMUG00000015590
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	2	NC_041755.1 (52893366..52914868, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	2	NC_027894.1 (137512657..137534480, complement)

Chromosome 2 - NC_041755.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

G54350 (e-PCR)
- UniSTS:146771

SIAH2_2129 (e-PCR)
- UniSTS:280996

SHGC-32660 (e-PCR)
- UniSTS:45561

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ubiquitin conjugating enzyme binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ubiquitin protein ligase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in multicellular organism development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: E3 ubiquitin-protein ligase SIAH2

Names: seven in absentia homolog 2

NP_001181312.1

EC 2.3.2.27

EC 6.3.2.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001194383.3 → NP_001181312.1 E3 ubiquitin-protein ligase SIAH2

See identical proteins and their annotated locations for NP_001181312.1

Status: PROVISIONAL

Source sequence(s)

QNVO02000280

UniProtKB/TrEMBL

F6TED2, H9FBV6

Related

ENSMMUP00000020449.2, ENSMMUT00000021864.4

Conserved Domains (2) summary

cd16752
Location:78 → 115

RING-HC_SIAH2; RING finger, HC subclass, found in seven in absentia homolog 2 (SIAH2) and similar proteins

pfam03145
Location:122 → 318

Sina; Seven in absentia protein family