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    Plac9 placenta specific 9 [ Mus musculus (house mouse) ]

    Gene ID: 211623, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Plac9provided by MGI
    Official Full Name
    placenta specific 9provided by MGI
    Primary source
    MGI:MGI:2663998
    See related
    Ensembl:ENSMUSG00000095304 AllianceGenome:MGI:2663998
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm9780; Plac9a; Plac9b; Gm10393
    Summary
    Predicted to be located in extracellular region. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sternum. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in lung adult (RPKM 185.1), subcutaneous fat pad adult (RPKM 170.7) and 17 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Plac9 in Genome Data Viewer
    Location:
    14 A3; 14 15.41 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (25888356..25903339, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (25888403..25902893, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_36222 Neighboring gene zinc finger, CCHC domain containing 24 Neighboring gene STARR-positive B cell enhancer mm9_chr14:26567064-26567365 Neighboring gene STARR-seq mESC enhancer starr_36224 Neighboring gene STARR-seq mESC enhancer starr_36226 Neighboring gene STARR-seq mESC enhancer starr_36227 Neighboring gene annexin A11 Neighboring gene predicted gene, 57811 Neighboring gene transmembrane protein 254 Neighboring gene eukaryotic translation elongation factor 1 gamma pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Placenta-specific 9, a putative secretory protein, induces G2/M arrest and inhibits the proliferation of human embryonic hepatic cells. Ouyang C, et al. Biosci Rep, 2018 Dec 21. PMID 30291214, Free PMC Article
    2. Plac8 and Plac9, novel placental-enriched genes identified through microarray analysis. Galaviz-Hernandez C, et al. Gene, 2003 May 8. PMID 12758124
    3. Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Naiman N, et al. Dev Cell, 2017 May 22. PMID 28535371, Free PMC Article
    4. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579
    5. Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. Abonnenc M, et al. Circ Res, 2013 Oct 25. PMID 24006456

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC41689

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    placenta-specific protein 9
    Names
    placenta specific 9a
    placenta specific 9b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207229.3 → NP_997112.1  placenta-specific protein 9 precursor

      See identical proteins and their annotated locations for NP_997112.1

      Status: VALIDATED

      Source sequence(s)
      AC165285
      Consensus CDS
      CCDS36832.1
      UniProtKB/Swiss-Prot
      Q3V2D9, Q8K262
      Related
      ENSMUSP00000056665.8, ENSMUST00000052286.16
      Conserved Domains (1) summary
      pfam15205
      Location:37 → 106
      PLAC9; Placenta-specific protein 9

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      25888356..25903339 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001270503.1: Suppressed sequence

      Description
      NM_001270503.1: This RefSeq was removed because it was redundant with NM_207229.1 after a merge.

    2. NM_001374766.1: Suppressed sequence

      Description
      NM_001374766.1: This RefSeq was removed because it was redundant with NM_207229.1 after a merge.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8K262.1 GenPept UniProtKB/Swiss-Prot:Q8K262

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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