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    Slc25a35 solute carrier family 25, member 35 [ Mus musculus (house mouse) ]

    Gene ID: 71998, updated on 3-Apr-2024

    Summary

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    Official Symbol
    Slc25a35provided by MGI
    Official Full Name
    solute carrier family 25, member 35provided by MGI
    Primary source
    MGI:MGI:1919248
    See related
    Ensembl:ENSMUSG00000018740 AllianceGenome:MGI:1919248
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1810012H11Rik
    Summary
    Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; olfactory epithelium; and thymus. Orthologous to human SLC25A35 (solute carrier family 25 member 35). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in mammary gland adult (RPKM 33.7), ovary adult (RPKM 32.6) and 18 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    11 B3; 11 42.24 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (68858954..68863342)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (68968096..68972516)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene Rho guanine nucleotide exchange factor 15 Neighboring gene predicted gene, 51902 Neighboring gene STARR-positive B cell enhancer ABC_E8415 Neighboring gene predicted gene, 32273 Neighboring gene STARR-positive B cell enhancer ABC_E2994 Neighboring gene STARR-positive B cell enhancer ABC_E11482 Neighboring gene RAN guanine nucleotide release factor Neighboring gene predicted gene, 32384 Neighboring gene phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) Neighboring gene microRNA 3062

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. Sundberg JP, et al. PLoS One, 2017. PMID 28700664, Free PMC Article
    2. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    3. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
    4. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    5. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    solute carrier family 25 member 35

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001418040.1 → NP_001404969.1  solute carrier family 25 member 35 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL603662

    2. NM_001418041.1 → NP_001404970.1  solute carrier family 25 member 35 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL603662

    3. NM_001418042.1 → NP_001404971.1  solute carrier family 25 member 35 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL603662
      UniProtKB/Swiss-Prot
      Q3TBP2, Q5SWT3, Q99KM5, Q9D913

    4. NM_001418043.1 → NP_001404972.1  solute carrier family 25 member 35 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL603662

    5. NM_028048.3 → NP_082324.1  solute carrier family 25 member 35 isoform 1

      See identical proteins and their annotated locations for NP_082324.1

      Status: VALIDATED

      Source sequence(s)
      AL603662
      Consensus CDS
      CCDS24874.1
      UniProtKB/Swiss-Prot
      Q3TBP2, Q5SWT3, Q99KM5, Q9D913
      UniProtKB/TrEMBL
      A0A0A0MQ70
      Related
      ENSMUSP00000099666.4, ENSMUST00000102606.10
      Conserved Domains (1) summary
      pfam00153
      Location:2 → 84
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      68858954..68863342
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5SWT3.2 GenPept UniProtKB/Swiss-Prot:Q5SWT3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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