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    ANKRD28 ankyrin repeat domain 28 [ Homo sapiens (human) ]

    Gene ID: 23243, updated on 7-Apr-2024

    Summary

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    Official Symbol
    ANKRD28provided by HGNC
    Official Full Name
    ankyrin repeat domain 28provided by HGNC
    Primary source
    HGNC:HGNC:29024
    See related
    Ensembl:ENSG00000206560 MIM:611122; AllianceGenome:HGNC:29024
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PITK; FAP79; CFAP79; PPP1R65
    Summary
    Predicted to be located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in bone marrow (RPKM 14.3), testis (RPKM 10.7) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    Location:
    3p25.1
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (15667236..15859814, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (15669546..15862982, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (15708743..15901321, complement)

    Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene collagen like tail subunit of asymmetric acetylcholinesterase Neighboring gene RNA, 7SL, cytoplasmic 110, pseudogene Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:15642981-15643623 Neighboring gene 2-hydroxyacyl-CoA lyase 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:15688189-15688722 Neighboring gene Sharpr-MPRA regulatory region 6531 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_65637 Neighboring gene biotinidase Neighboring gene microRNA 3134 Neighboring gene uncharacterized LOC101927647 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14108 Neighboring gene RNA, 7SL, cytoplasmic 4, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19535 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14109 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19536 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19537 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19538 Neighboring gene H3K27ac hESC enhancer GRCh37_chr3:15887901-15888400 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14110 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14111 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14112 Neighboring gene uncharacterized LOC107986064 Neighboring gene inosine monophosphate dehydrogenase 1 pseudogene 8 Neighboring gene microRNA 563

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. circANKRD28 inhibits cisplatin resistance in non-small-cell lung cancer through the miR-221-3p/SOCS3 axis. Song S, et al. J Gene Med, 2023 Apr. PMID 36740786
    2. [Effect of hnRNP K and its interaction with HPV16 on cervical intraepithelial neoplasia]. Ding L, et al. Zhonghua Liu Xing Bing Xue Za Zhi, 2018 Dec 10. PMID 30572391
    3. Regulation of focal adhesion and cell migration by ANKRD28-DOCK180 interaction. Kiyokawa E, et al. Cell Adh Migr, 2009 Jul-Sep. PMID 19458477, Free PMC Article
    4. Dual kinase-mediated regulation of PITK by CaMKII and GSK3. Kwiek NC, et al. Cell Signal, 2007 Mar. PMID 17023142
    5. Ankyrin repeat domain 28 (ANKRD28), a novel binding partner of DOCK180, promotes cell migration by regulating focal adhesion formation. Tachibana M, et al. Exp Cell Res, 2009 Mar 10. PMID 19118547

    See all (90) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. circANKRD28 inhibits cisplatin resistance in non-small-cell lung cancer through the miR-221-3p/SOCS3 axis.
      Title: circANKRD28 inhibits cisplatin resistance in non-small-cell lung cancer through the miR-221-3p/SOCS3 axis.
    2. HPV16 infection and over-expression of hnRNP K protein were associated with the increased risk of cervical intraepithelial neoplasia. There might be interaction between hnRNP K protein overexpression and HPV16 infection existed on the progress of CIN/ [ cervical intraepithelial neoplasia II/III].
      Title: [Effect of hnRNP K and its interaction with HPV16 on cervical intraepithelial neoplasia].
    3. findings suggest that BRCA1 is a novel modulator of PP6 signalling via its interaction with ANKRD28.
      Title: BRCA1 affects protein phosphatase 6 signalling through its interaction with ANKRD28.
    4. hnRNP K and hnRNP L may serve as A1CF-like cofactors in AID-mediated class switch recombination and somatic hypermutation
      Title: Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase.
    5. ANKRD28, a novel binding partner of DOCK180, promotes cell migration by regulating focal adhesion formation.
      Title: Ankyrin repeat domain 28 (ANKRD28), a novel binding partner of DOCK180, promotes cell migration by regulating focal adhesion formation.
    6. CaMKII and GSK3 mediate regulation of PITK.
      Title: Dual kinase-mediated regulation of PITK by CaMKII and GSK3.
    7. These findings provide a putative mechanism by which transcriptional activity of hnRNP K can be discretely controlled through the regulation of PP1 activity.
      Title: PITK, a PP1 targeting subunit that modulates the phosphorylation of the transcriptional regulator hnRNP K.
    Submit: New GeneRIF Correction

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA0379

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    		  

    General protein information

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    Preferred Names
    serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
    Names
    PP6-ARS-A
    ankyrin repeat domain-containing protein 28
    phosphatase interactor targeting K protein
    phosphatase interactor targeting protein hnRNP K
    protein phosphatase 1, regulatory subunit 65
    protein phosphatase 6 ankyrin repeat subunit A
    serine/threonine-protein phosphatase 6 regulatory subunit ARS-A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001195098.1 → NP_001182027.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform b

      See identical proteins and their annotated locations for NP_001182027.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2), as well as variants 3 and 10, encodes isoform b.
      Source sequence(s)
      AC090950, AK293770, AY367056, BQ423818
      Consensus CDS
      CCDS74908.1
      UniProtKB/Swiss-Prot
      O15084
      Related
      ENSP00000485421.1, ENST00000624145.3
      Conserved Domains (6) summary
      PHA02874
      Location:400 → 709
      PHA02874; ankyrin repeat protein; Provisional
      PHA03095
      Location:65 → 321
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:22 → 49
      ANK; ANK repeat [structural motif]
      pfam00023
      Location:773 → 803
      Ank; Ankyrin repeat
      pfam12796
      Location:673 → 766
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:1 → 116
      Ank_2; Ankyrin repeats (3 copies)

    2. NM_001195099.2 → NP_001182028.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform b

      See identical proteins and their annotated locations for NP_001182028.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3), as well as variants 2 and 10, encodes isoform b.
      Source sequence(s)
      AC090950, AK293770, AY367056, BQ423818
      Consensus CDS
      CCDS74908.1
      UniProtKB/Swiss-Prot
      O15084
      Conserved Domains (6) summary
      PHA02874
      Location:400 → 709
      PHA02874; ankyrin repeat protein; Provisional
      PHA03095
      Location:65 → 321
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:22 → 49
      ANK; ANK repeat [structural motif]
      pfam00023
      Location:773 → 803
      Ank; Ankyrin repeat
      pfam12796
      Location:673 → 766
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:1 → 116
      Ank_2; Ankyrin repeats (3 copies)

    3. NM_001349277.2 → NP_001336206.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) encodes isoform c.
      Source sequence(s)
      AC090950
      Conserved Domains (5) summary
      PHA02874
      Location:587 → 896
      PHA02874; ankyrin repeat protein; Provisional
      PHA03095
      Location:55 → 343
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:173 → 203
      ANK; ANK repeat [structural motif]
      pfam00023
      Location:960 → 990
      Ank; Ankyrin repeat
      pfam12796
      Location:860 → 953
      Ank_2; Ankyrin repeats (3 copies)

    4. NM_001349278.2 → NP_001336207.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) encodes isoform d.
      Source sequence(s)
      AC090950
      Consensus CDS
      CCDS93222.1
      Related
      ENSP00000508086.1, ENST00000683139.1
      Conserved Domains (5) summary
      PHA02874
      Location:584 → 893
      PHA02874; ankyrin repeat protein; Provisional
      PHA03095
      Location:52 → 340
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:170 → 200
      ANK; ANK repeat [structural motif]
      pfam00023
      Location:957 → 987
      Ank; Ankyrin repeat
      pfam12796
      Location:857 → 950
      Ank_2; Ankyrin repeats (3 copies)

    5. NM_001349279.2 → NP_001336208.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) encodes isoform e.
      Source sequence(s)
      AC090945, AC090950
      Conserved Domains (5) summary
      PHA02874
      Location:551 → 860
      PHA02874; ankyrin repeat protein; Provisional
      PHA03095
      Location:19 → 307
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:137 → 167
      ANK; ANK repeat [structural motif]
      pfam00023
      Location:924 → 954
      Ank; Ankyrin repeat
      pfam12796
      Location:824 → 917
      Ank_2; Ankyrin repeats (3 copies)

    6. NM_001349280.1 → NP_001336209.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform f

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7), as well as variants 8 and 9, encodes isoform f.
      Source sequence(s)
      AC090950
      Conserved Domains (5) summary
      cd00204
      Location:78 → 203
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:84 → 114
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:319 → 360
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:483 → 534
      Ank_5; Ankyrin repeats (many copies)
      cl26073
      Location:30 → 303
      Ank_2; Ankyrin repeats (3 copies)

    7. NM_001349281.2 → NP_001336210.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform f

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8), as well as variants 7 and 9, encodes isoform f.
      Source sequence(s)
      AC090950
      Conserved Domains (5) summary
      cd00204
      Location:78 → 203
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:84 → 114
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:319 → 360
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:483 → 534
      Ank_5; Ankyrin repeats (many copies)
      cl26073
      Location:30 → 303
      Ank_2; Ankyrin repeats (3 copies)

    8. NM_001349282.2 → NP_001336211.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform f

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9), as well as variants 7 and 8, encodes isoform f.
      Source sequence(s)
      AC090950
      Conserved Domains (5) summary
      cd00204
      Location:78 → 203
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:84 → 114
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:319 → 360
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:483 → 534
      Ank_5; Ankyrin repeats (many copies)
      cl26073
      Location:30 → 303
      Ank_2; Ankyrin repeats (3 copies)

    9. NM_001349283.2 → NP_001336212.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10), as well as variants 2 and 3, encodes isoform b.
      Source sequence(s)
      AC090950
      Consensus CDS
      CCDS74908.1
      Conserved Domains (6) summary
      PHA02874
      Location:400 → 709
      PHA02874; ankyrin repeat protein; Provisional
      PHA03095
      Location:65 → 321
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:22 → 49
      ANK; ANK repeat [structural motif]
      pfam00023
      Location:773 → 803
      Ank; Ankyrin repeat
      pfam12796
      Location:673 → 766
      Ank_2; Ankyrin repeats (3 copies)
      cl39094
      Location:1 → 116
      Ank_2; Ankyrin repeats (3 copies)

    10. NM_001349284.2 → NP_001336213.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform g

      Status: VALIDATED

      Description
      Transcript Variant: This variant (11) encodes isoform g.
      Source sequence(s)
      AC090950

    11. NM_001349285.2 → NP_001336214.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform h

      Status: VALIDATED

      Description
      Transcript Variant: This variant (12) encodes isoform h.
      Source sequence(s)
      AC090950
      Related
      ENST00000461696.1

    12. NM_015199.4 → NP_056014.2  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform a

      See identical proteins and their annotated locations for NP_056014.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform a.
      Source sequence(s)
      AC090945, AC090950, AI565587, AK293770, AY367056, BQ423818, CN313636
      Consensus CDS
      CCDS46769.1
      UniProtKB/Swiss-Prot
      B4DES5, O15084, Q1WWL4, Q29RW6, Q3B857, Q6ULS0, Q6ZT57
      Related
      ENSP00000382379.2, ENST00000399451.6
      Conserved Domains (5) summary
      PHA02874
      Location:554 → 863
      PHA02874; ankyrin repeat protein; Provisional
      PHA03095
      Location:22 → 310
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:140 → 170
      ANK; ANK repeat [structural motif]
      pfam00023
      Location:927 → 957
      Ank; Ankyrin repeat
      pfam12796
      Location:827 → 920
      Ank_2; Ankyrin repeats (3 copies)

    RNA

    1. NR_146111.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC090950

    2. NR_146112.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC090950

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

      Range
      15667236..15859814 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047447807.1 → XP_047303763.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X10

    2. XM_011533542.4 → XP_011531844.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X4

      See identical proteins and their annotated locations for XP_011531844.1

      Conserved Domains (6) summary
      cd00204
      Location:619 → 748
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:112 → 142
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:414 → 498
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:900 → 951
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:511 → 562
      Ank_5; Ankyrin repeats (many copies)
      cl26073
      Location:6 → 273
      Ank_2; Ankyrin repeats (3 copies)

    3. XM_024453422.2 → XP_024309190.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

      Conserved Domains (5) summary
      cd00204
      Location:78 → 203
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:84 → 114
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:319 → 360
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:483 → 534
      Ank_5; Ankyrin repeats (many copies)
      cl26073
      Location:30 → 303
      Ank_2; Ankyrin repeats (3 copies)

    4. XM_047447809.1 → XP_047303765.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X12

    5. XM_047447810.1 → XP_047303766.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X13

    6. XM_024453419.2 → XP_024309187.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X2

      Conserved Domains (6) summary
      cd00204
      Location:658 → 787
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:151 → 181
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:453 → 537
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:939 → 990
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:550 → 601
      Ank_5; Ankyrin repeats (many copies)
      cl26073
      Location:33 → 321
      Ank_2; Ankyrin repeats (3 copies)

    7. XM_024453418.2 → XP_024309186.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1

      Conserved Domains (6) summary
      cd00204
      Location:661 → 790
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:154 → 184
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:456 → 540
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:942 → 993
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:553 → 604
      Ank_5; Ankyrin repeats (many copies)
      cl26073
      Location:36 → 324
      Ank_2; Ankyrin repeats (3 copies)

    8. XM_024453424.2 → XP_024309192.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

      Conserved Domains (5) summary
      cd00204
      Location:78 → 203
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:84 → 114
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:319 → 360
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:483 → 534
      Ank_5; Ankyrin repeats (many copies)
      cl26073
      Location:30 → 303
      Ank_2; Ankyrin repeats (3 copies)

    9. XM_047447805.1 → XP_047303761.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

    10. XM_047447804.1 → XP_047303760.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

    11. XM_011533547.4 → XP_011531849.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

      See identical proteins and their annotated locations for XP_011531849.1

      Conserved Domains (5) summary
      cd00204
      Location:78 → 203
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:84 → 114
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:319 → 360
      Ank_4; Ankyrin repeats (many copies)
      pfam13857
      Location:483 → 534
      Ank_5; Ankyrin repeats (many copies)
      cl26073
      Location:30 → 303
      Ank_2; Ankyrin repeats (3 copies)

    12. XM_047447803.1 → XP_047303759.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X7

    13. XM_047447802.1 → XP_047303758.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X6

    14. XM_047447813.1 → XP_047303769.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X16

    15. XM_047447806.1 → XP_047303762.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X9

    16. XM_047447808.1 → XP_047303764.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X11

    17. XM_047447801.1 → XP_047303757.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X5

    18. XM_047447800.1 → XP_047303756.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X3

    19. XM_047447811.1 → XP_047303767.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X14

    20. XM_047447812.1 → XP_047303768.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X15

    RNA

    1. XR_007095653.1 RNA Sequence

    2. XR_007095652.1 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060927.1 Alternate T2T-CHM13v2.0

      Range
      15669546..15862982 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054345869.1 → XP_054201844.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X10

    2. XM_054345859.1 → XP_054201834.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X4

    3. XM_054345867.1 → XP_054201842.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

    4. XM_054345871.1 → XP_054201846.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X12

    5. XM_054345872.1 → XP_054201847.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X13

    6. XM_054345857.1 → XP_054201832.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X2

    7. XM_054345856.1 → XP_054201831.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1

    8. XM_054345865.1 → XP_054201840.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

    9. XM_054345864.1 → XP_054201839.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

    10. XM_054345863.1 → XP_054201838.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

    11. XM_054345866.1 → XP_054201841.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X8

    12. XM_054345862.1 → XP_054201837.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X7

    13. XM_054345861.1 → XP_054201836.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X6

    14. XM_054345875.1 → XP_054201850.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X16

    15. XM_054345868.1 → XP_054201843.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X9

    16. XM_054345870.1 → XP_054201845.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X11

    17. XM_054345860.1 → XP_054201835.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X5

    18. XM_054345858.1 → XP_054201833.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X3

    19. XM_054345873.1 → XP_054201848.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X14

    20. XM_054345874.1 → XP_054201849.1  serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X15

    RNA

    1. XR_008486682.1 RNA Sequence

    2. XR_008486681.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O15084.5 GenPept UniProtKB/Swiss-Prot:O15084

    Gene LinkOut

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