Mcur1 mitochondrial calcium uniporter regulator 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Mcur1provided by RGD
Official Full Name: mitochondrial calcium uniporter regulator 1provided by RGD
Primary source: RGD:1307673
See related: AllianceGenome:RGD:1307673
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Ccdc90a; RGD1307673
Summary: Predicted to be involved in calcium import into the mitochondrion and positive regulation of mitochondrial calcium ion concentration. Predicted to be active in mitochondrion. Predicted to be integral component of mitochondrial inner membrane. Orthologous to human MCUR1 (mitochondrial calcium uniporter regulator 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Kidney (RPKM 106.1), Thymus (RPKM 55.9) and 9 other tissues See more
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 17p14

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	17	NC_086035.1 (21348490..21365614)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	17	NC_051352.1 (21142526..21159651)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	17	NC_005116.4 (24165259..24182425, complement)

Chromosome 17 - NC_086035.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

BQ202174 (e-PCR)
- UniSTS:260706

RH131119 (e-PCR)
- UniSTS:214402

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in calcium import into the mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
involved_in calcium import into the mitochondrion	ISO Inferred from Sequence Orthology more info
involved_in calcium ion import	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial calcium ion transmembrane transport	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of mitochondrial calcium ion concentration	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of mitochondrial calcium ion concentration	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in mitochondrial inner membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrial inner membrane	ISO Inferred from Sequence Orthology more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: mitochondrial calcium uniporter regulator 1

Names: coiled-coil domain containing 90A; coiled-coil domain-containing protein 90A, mitochondrial

NP_001292107.1

EC 1.1.1.41

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001305178.1 → NP_001292107.1 mitochondrial calcium uniporter regulator 1

See identical proteins and their annotated locations for NP_001292107.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000017

UniProtKB/TrEMBL

A6J744

Conserved Domains (1) summary

pfam07798
Location:143 → 334

DUF1640; Protein of unknown function (DUF1640)