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    Nup58 Nucleoporin 58kD [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42342, updated on 10-May-2024

    Summary

    Official Symbol
    Nup58provided by FlyBase
    Official Full Name
    Nucleoporin 58kDprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038722
    Locus tag
    Dmel_CG7360
    See related
    AllianceGenome:FB:FBgn0038722
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG7360; Dm NUP58; Dmel\CG7360; nup58; RE52572p
    Summary
    Predicted to enable nuclear localization sequence binding activity. Predicted to be a structural constituent of nuclear pore. Predicted to be involved in nucleocytoplasmic transport. Located in nuclear envelope. Is expressed in adult head and organism. Orthologous to human NUP58 (nucleoporin 58). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See Nup58 in Genome Data Viewer
    Location:
    92A11-92A11; 3-66 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (19645026..19646906)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15470748..15472628)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene subdued Neighboring gene uncharacterized protein Neighboring gene Vacuolar H[+] ATPase 13kD subunit Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables nuclear localization sequence binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables nuclear localization sequence binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of nuclear pore IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of nuclear pore ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in nucleocytoplasmic transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in nucleocytoplasmic transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of nuclear pore IEA
    Inferred from Electronic Annotation
    more info
     
    part_of nuclear pore ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    nucleoporin 58kD
    Names
    CG7360-PA
    Nup58-PA
    nucleoporin 58

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      19645026..19646906
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142564.4NP_650821.2  nucleoporin 58kD [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650821.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8SYM7, Q9VDV3
      Related
      FBpp0083195
      Conserved Domains (2) summary
      PHA03247
      Location:25195
      PHA03247; large tegument protein UL36; Provisional
      pfam15967
      Location:136525
      Nucleoporin_FG2; Nucleoporin FG repeated region