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    CCL4 C-C motif chemokine ligand 4 [ Bos taurus (cattle) ]

    Gene ID: 414347, updated on 4-Feb-2024

    Summary

    Gene symbol
    CCL4
    Gene description
    C-C motif chemokine ligand 4
    See related
    BGD:BT10109; Ensembl:ENSBTAG00000025257
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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    Genomic context

    Location:
    chromosome: 19
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (14339697..14341265, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene WAP four-disulfide core domain protein 18 Neighboring gene WAP four-disulfide core domain protein 18 Neighboring gene protein RUFY3-like Neighboring gene chemokine (C-C motif) ligand 3

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables CCR chemokine receptor binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables chemokine activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in cellular response to interleukin-1 IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in cellular response to tumor necrosis factor IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in cellular response to type II interferon IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in chemokine-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in lymphocyte chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in monocyte chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in neutrophil chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in positive regulation of ERK1 and ERK2 cascade IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    C-C motif chemokine 4
    Names
    chemokine (C-C motif) ligand 4
    putative MIP1-beta protein
    small-inducible cytokine A4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075147.2NP_001068615.1  C-C motif chemokine 4 precursor

      See identical proteins and their annotated locations for NP_001068615.1

      Status: PROVISIONAL

      Source sequence(s)
      BC118471
      UniProtKB/Swiss-Prot
      Q17QA1
      Related
      ENSBTAP00000009446.4, ENSBTAT00000009446.5
      Conserved Domains (1) summary
      pfam00048
      Location:3286
      IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      14339697..14341265 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)