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    IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha [ Bos taurus (cattle) ]

    Gene ID: 282446, updated on 5-Mar-2024

    Summary

    Official Symbol
    IDH3Aprovided by VGNC
    Official Full Name
    isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alphaprovided by VGNC
    Primary source
    VGNC:VGNC:53942
    See related
    BGD:BT10615; Ensembl:ENSBTAG00000006227
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    BG1
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    Location:
    chromosome: 21
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 21 NC_037348.1 (30538337..30554570)

    Chromosome 21 - NC_037348.1Genomic Context describing neighboring genes Neighboring gene SH2 domain containing 7 Neighboring gene calcium and integrin binding family member 2 Neighboring gene acyl-CoA synthetase bubblegum family member 1 Neighboring gene uncharacterized LOC132343357

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037348.1 Chromosome 21 Reference ARS-UCD2.0 Primary Assembly

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • KIAA0631, MGC139736

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables isocitrate dehydrogenase (NAD+) activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in isocitrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in tricarboxylic acid cycle IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
    Names
    NAD(+)-specific ICDH subunit alpha
    isocitrate dehydrogenase (NAD(+)) 3 alpha
    isocitrate dehydrogenase 3 (NAD(+)) alpha
    isocitrate dehydrogenase 3 (NAD+) alpha
    isocitrate dehydrogenase subunits 3/4
    isocitric dehydrogenase subunit alpha
    NP_777069.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174644.2NP_777069.1  isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial precursor

      See identical proteins and their annotated locations for NP_777069.1

      Status: PROVISIONAL

      Source sequence(s)
      U07980
      UniProtKB/Swiss-Prot
      P41563
      Related
      ENSBTAP00000008177.4, ENSBTAT00000008177.5
      Conserved Domains (1) summary
      TIGR00175
      Location:29362
      mito_nad_idh; isocitrate dehydrogenase, NAD-dependent, mitochondrial type

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037348.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      30538337..30554570
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)