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    cut-2 Cuticlin 2 [ Caenorhabditis elegans ]

    Gene ID: 179823, updated on 7-Sep-2023

    Summary

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    Gene symbol
    cut-2
    Gene description
    Cuticlin 2
    Primary source
    WormBase:WBGene00009983
    Locus tag
    CELE_F53F1.5
    See related
    AllianceGenome:WB:WBGene00009983
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of cuticle. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: V
    Exon count:
    2
    Sequence:
    Chromosome: V; NC_003283.11 (13414949..13416064)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Protein containing ALS2cr12 (ALS2CR12) signature Neighboring gene Serpentine Receptor, class V

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Activity of albendazole-ivermectin combination and other filaricidal drugs against infective larvae, preadult, microfilariae and adult worms of Molinema dessetae in the rodent Proechimys oris. Duarte Z, et al. Parasite, 1994 Mar. PMID 9140472
    2. Assembly of nematode cuticle: role of hydrophobic interactions in CUT-2 cross-linking. Parise G, et al. Biochim Biophys Acta, 1997 Feb 8. PMID 9048907
    3. Ultrastructural immuno-localization of CUT-1 and CUT-2 antigenic sites in the cuticles of the nematode Caenorhabditis elegans. Ristoratore F, et al. J Submicrosc Cytol Pathol, 1994 Jul. PMID 8087805
    4. The role of dityrosine formation in the crosslinking of CUT-2, the product of a second cuticlin gene of Caenorhabditis elegans. Lassandro F, et al. Mol Biochem Parasitol, 1994 May. PMID 7935621
    5. Caenorhabditis elegans as a model for parasitic nematodes: a focus on the cuticle. Politz SM, et al. Parasitol Today, 1992 Jan. PMID 15463517

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of cuticle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cortical layer of collagen and cuticulin-based cuticle extracellular matrix NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cuticlin 2
    NP_506325.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      13414949..13416064
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073924.5 → NP_506325.1  Cuticlin 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506325.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34682
    Nucleotide Protein
    Heading Accession and Version

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